Results 41 to 50 of about 57,349 (269)

Protein interactions in Xenopus germ plasm RNP particles [PDF]

, 2013
Hermes is an RNA-binding protein that we have previously reported to be found in the ribonucleoprotein (RNP) particles of Xenopus germ plasm, where it is associated with various RNAs, including that encoding the germ line determinant Nanos1.
A Anyanful, A Mir, AM Hulstrand, AT Hertig, Barbara Bardoni, C Hudson, C Yost, CA Schneider, CD Hu, D Jin, DL Gard, F Bontems, F Lai, FF Lai, FL Marlow, GT Morgan, Hugh R. Woodland, HW Song, HY Li, I Yanai, J Heasman, JB Bowes, JK Joung, JK Yisraeli, K Kosaka, KL Poon, LA Berekelya, M Claussen, M Kloc, M Kloc, ML King, NP Torpey, P Anderson, RJ Machado, RS Hames, S Miyamoto, S Nijjar, Sarbjit Nijjar, SM Bilinski, T Fukuda, TK Kerppola, WV Gerber, WV Gerber, Y Saka, Y Zhou, ZF Nizami   +45 more
core   +7 more sources

Heterologous saRNA Prime, DNA Dual-Antigen Boost SARS-CoV-2 Vaccination Elicits Robust Cellular Immunogenicity and Cross-Variant Neutralizing Antibodies

Frontiers in Immunology, 2022
We assessed if immune responses are enhanced in CD-1 mice by heterologous vaccination with two different nucleic acid-based COVID-19 vaccines: a next-generation human adenovirus serotype 5 (hAd5)-vectored dual-antigen spike (S) and nucleocapsid (N ...
Adrian Rice, Mohit Verma, Emily Voigt, Peter Battisti, Sam Beaver, Sierra Reed, Kyle Dinkins, Shivani Mody, Lise Zakin, Shiho Tanaka, Brett Morimoto, C. Anders Olson, Elizabeth Gabitzsch, Jeffrey T. Safrit, Patricia Spilman, Corey Casper, Corey Casper, Patrick Soon-Shiong   +17 more
doaj   +1 more source

Lentiviral vectors with amplified beta cell-specific gene expression. [PDF]

, 2009
An important goal of gene therapy is to be able to deliver genes, so that they express in a pattern that recapitulates the expression of an endogenous cellular gene.
Crooks, GM, Ge, S, Hardee, C, Hollis, RP, Kohn, DB, Pais, E, Shaw, KL, Skelton, D   +7 more
core   +2 more sources

Maternal embryonic leucine zipper kinase (MELK) regulates multipotent neural progenitor proliferation. [PDF]

, 2005
Maternal embryonic leucine zipper kinase (MELK) was previously identified in a screen for genes enriched in neural progenitors. Here, we demonstrate expression of MELK by progenitors in developing and adult brain and that MELK serves as a marker for self-
Bajpai, Ruchi, Dougherty, Joseph D, Freije, William A, Geschwind, Daniel H, Groszer, Matthias, Imura, Tetsuya, Kelly, Theresa K, Kim, Kevin J, Kornblum, Harley I, Liu, Xin, Nakano, Ichiro, Nelson, Stanley F, Ou, Jing, Paucar, Andres A, Sofroniew, Michael V, Terskikh, Alexey V, Wu, Hong, Zewail, Amani   +17 more
core   +2 more sources

Template-dependent multiple displacement amplification for profiling human circulating RNA [PDF]

, 2017
Multiple displacement amplification (MDA) is widely used in whole-genome/transcriptome amplification. However, template-independent amplification (TIA) in MDA is a commonly observed phenomenon, particularly when using high concentrations of random ...
Crosby, Seth D, Di Bisceglie, Adrian M, Fan, Xiaofeng, Lu, Yang, Ren, Yi, Wang, Weihua, Xu, Yuan   +6 more
core   +2 more sources

Self-Amplifying RNA Viruses as RNA Vaccines

International Journal of Molecular Sciences, 2020
Single-stranded RNA viruses such as alphaviruses, flaviviruses, measles viruses and rhabdoviruses are characterized by their capacity of highly efficient self-amplification of RNA in host cells, which make them attractive vehicles for vaccine development.
openaire   +2 more sources

Perspectives on RNA Vaccine Candidates for COVID-19

Frontiers in Molecular Biosciences, 2021
With the current outbreak caused by SARS-CoV-2, vaccination is acclaimed as a public health care priority. Rapid genetic sequencing of SARS-CoV-2 has triggered the scientific community to search for effective vaccines.
Pobitra Borah, Pobitra Borah, Pran Kishore Deb, Nizar A. Al-Shar’i, Lina A. Dahabiyeh, Katharigatta N. Venugopala, Katharigatta N. Venugopala, Vinayak Singh, Vinayak Singh, Pottathil Shinu, Snawar Hussain, Satyendra Deka, Balakumar Chandrasekaran, Da’san M. M. Jaradat   +13 more
doaj   +1 more source

c-Src drives intestinal regeneration and transformation [PDF]

, 2014
The non‐receptor tyrosine kinase c‐Src, hereafter referred to as Src, is overexpressed or activated in multiple human malignancies. There has been much speculation about the functional role of Src in colorectal cancer (CRC), with Src amplification and ...
Cordero, Julia B., Frame, Margaret, Muller, William J., Nixon, Colin, Ridgway, Rachel A., Sansom, Owen J., Valeri, Nicola, Vidal, Marcos   +7 more
core   +3 more sources

Advances in saRNA Vaccine Research against Emerging/Re-Emerging Viruses

Vaccines, 2023
Although conventional vaccine approaches have proven to be successful in preventing infectious diseases in past decades, for vaccine development against emerging/re-emerging viruses, one of the main challenges is rapid response in terms of design and ...
Yalan Liu, Yuncheng Li, Qinxue Hu
doaj   +1 more source

Specific Preferences in Lineage Choice and Phenotypic Plasticity of Glioma Stem Cells Under BMP4 and Noggin Influence [PDF]

, 2015
Although BMP4-induced differentiation of glioma stem cells (GSCs) is well recognized, details of the cellular responses triggered by this morphogen are still poorly defined.
Arakaki, Naomi, Fernandez Espinosa, Damian Dario, Garcia, Carolina Paola, Martinetto, Horacio Enrique, Miriuka, Santiago Gabriel, Roisman, Alejandro, Romorini, Leonardo, Scassa, Maria Elida, Sevlever, Gustavo Emilio, Slavutsky, Irma Rosa, Videla Richardson, Guillermo Agustín   +10 more
core   +1 more source