Results 101 to 110 of about 2,098 (175)

Inactivation of the ERK1/2 and AKT pathways in SEMA7A knockdown cells.

, 2015
(A, B) Immunoblotting analysis shows that SEMA7A knockdown results in decreased levels of pERK1/2 and pAKT compared with the shMock cells (SAS and KOSC-2-derived transfectants).
Isao Miyamoto (797074), Takane Suzuki (797075), Manabu Iyoda (359431), Yosuke Endo-Sakamoto (359437), Masashi Shiiba (281853), Atsushi Kasamatsu (281849), Hideki Tanzawa (145219), Kengo Saito (593605), Katsuhiro Uzawa (145207), Tomoaki Saito (797073), Katsunori Ogawara (281852)   +10 more
core   +1 more source

Differential expression of Semaphorin-7A /CD163-positive macrophages in large artery and cardiogenic stroke

BMC Neurology
Background Identification of the causes of stroke of undetermined etiology, specifically cardioembolism (CE) and non-CE causes, can inform treatment planning and prognosis prediction. The objective of this study was to analyze the disparities in thrombus
Yi Jiang, Zhichao Sun, Zhonglin Ge, Zhonghai Tao, Mengqian Liu, Wen Zhong, Nan Dong, Lei Xu, Hui Wang, Yiwen Xu, Xiaozhu Shen   +10 more
doaj   +1 more source

Semaphorin 7A contributes to TGF-β-mediated liver fibrogenesis

, 2013
Semaphorin7A (SEMA7A) is a membrane-anchored protein involved in immune and inflammatory responses, exerting an effect on pulmonary fibrosis. Thus, we aimed to investigate the role of SEMA7A in hepatic fibrosis. Liver injury was induced in vivo by carbon
De Minicis S, Saccomanno S, Bataller R, Millán C, Rychlicki C, Trozzi L, Candelaresi C, MARZIONI, MARCO, BENEDETTI, Antonio, Agostinelli L, Svegliati Baroni G., MOCCHEGIANI, FEDERICO, Brenner DA, VIVARELLI, MARCO   +13 more
core   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Image_1_Semaphorin 7A Promotes VEGFA/VEGFR2-Mediated Angiogenesis and Intraplaque Neovascularization in ApoE-/- Mice.tif

, 2018
Excessive neovascularization of atherosclerotic lesions increases plaque vulnerability and the susceptibility to rupture. Semaphorin 7A (Sema7A), a semaphorin family member, was recently reported to promote atherosclerotic plaque formation by mediating d-
Tao You (181123), Shuhong Hu (1632217), Yifei Liu (547021), Li Zhu (67404)   +3 more
core   +1 more source

Semaphorin 7A Is a Negative Regulator of T Cell Responses

, 2006
SummarySemaphorins play an essential role in axonal guidance, and emerging evidence points to diverse functions of several Semaphorin family members in the immune system. Semaphorin 7A (Sema7A) promotes axonal growth in the central nervous system.
Czopik, Agnieszka K., Palm, Noah, Bynoe, Margaret S., Raine, Cedric S., Medzhitov, Ruslan   +4 more
core   +1 more source

Image_3_Semaphorin 7A Promotes VEGFA/VEGFR2-Mediated Angiogenesis and Intraplaque Neovascularization in ApoE-/- Mice.tif

, 2018
Excessive neovascularization of atherosclerotic lesions increases plaque vulnerability and the susceptibility to rupture. Semaphorin 7A (Sema7A), a semaphorin family member, was recently reported to promote atherosclerotic plaque formation by mediating d-
Tao You (181123), Shuhong Hu (1632217), Yifei Liu (547021), Li Zhu (67404)   +3 more
core   +1 more source

Semaphorins: Novel Insights on Their Emerging Multifaceted Roles in the Evolving Landscape of Breast Cancer

Acta Medica Bulgarica
Semaphorins, initially identified as phylogenetically conserved axon guidance molecules, comprise an extracellular signaling protein family involved in various biological events that regulate the development, tissue homeostasis and cancer progression of ...
Popov Ts.
doaj   +1 more source

Effect of substrate reduction therapy with Eliglustat on red blood cell properties in type 1 Gaucher disease

Discover Medicine
Background Type 1 Gaucher disease (GD) is a lysosomal storage disorder characterized by splenomegaly, lipid-laden macrophage accumulation (Gaucher cells), and complex skeletal involvement, though its pathophysiology remains incompletely understood.
Meriem Daho, Ali Tawbeh, Sandrine Genetet, Emmanuelle Bourdelier, Kaouther Ben Arfa Haddad, Terkia Bettioui, Marine de Person, Benedicte Hivert, Nadia Belmatoug, Mélanie Franco   +9 more
doaj   +1 more source

Identification and validation of immune-related biomarkers for sepsis-induced acute respiratory distress syndrome

Zhongguo linchuang yanjiu
Objective To provide a scientific basis for understanding the disease mechanism and achieving precise diagnosis and treatment of sepsis-induced acute respiratory distress syndrome（ARDS）related to immune imbalance by identifying immune regulation-related ...
XIONG Yaxin*,MAO Yuqi,GU Quankuan,ZHAO Mingyan,MENG Xianglin
doaj   +1 more source