Results 31 to 40 of about 910 (176)

Interplay in neural functions of cell adhesion molecule close homolog of L1 (CHL1) and Programmed Cell Death 6 (PDCD6)

FASEB BioAdvances, Volume 4, Issue 1, Page 43-59, January 2022., 2022
Abstract Close homolog of L1 (CHL1) is a cell adhesion molecule of the immunoglobulin superfamily. It promotes neuritogenesis and survival of neurons in vitro. In vivo, CHL1 promotes nervous system development, regeneration after trauma, and synaptic function and plasticity.
Gabriele Loers, Thomas Theis, Helen Baixia Hao, Ralf Kleene, Sanjana Arsha, Nina Samuel, Neha Arsha, Wise Young, Melitta Schachner   +8 more
wiley   +1 more source

[Retracted] Impact of Yiqi Huoxue Decoction on the Relationship between Remodeling of Cardiac Nerves and Macrophages after Myocardial Infarction in Rats

Journal of Healthcare Engineering, Volume 2022, Issue 1, 2022., 2022
Sympathetic nerve remodeling after myocardial infarction (MI) has an indispensable role in cardiac remodeling. Numerous works have shown that sympathetic nerve remodeling can be delayed by inhibition of inflammatory response. Earlier studies have shown improvement in ventricular remodeling and inhibited chronic stage neural remodeling by Yiqi Huoxue ...
Yunke Liu, Shunwen Guo, Yuqin Zhang, Hui Wang, Jiani Wu, Wang’ou Lin, Binyue Zhang, Jie Chen, Yufei Li, Yunshu Zhang, Fanyu Wei, Tianhui Du, Liaqat Ali   +12 more
wiley   +1 more source

A re‐innervated in vitro skin model of non‐histaminergic itch and skin neurogenic inflammation: PAR2‐, TRPV1‐ and TRPA1‐agonist induced functionality

Skin Health and Disease, Volume 1, Issue 4, December 2021., 2021
Abstract Background Skin, and epidermis, is innervated by sensory nerve fibres. Interactions between them and signal transduction are only partially elucidated in physiological/pathological conditions, especially in pruritus. Objectives To study the mechanisms involved in pruritus in vitro, we developed a skin explant model re‐innervated by sensory ...
N. Lebonvallet, J. W. Fluhr, C. Le Gall‐Ianotto, R. Leschiera, M. Talagas, A. Reux, A. Bataille, C. Brun, T. Oddos, J.‐P. Pennec, J.‐L. Carré, L. Misery   +11 more
wiley   +1 more source

Semaphorin3A Promotes the Development of Nickel Allergy [PDF]

, 2021
Abstract Metal allergy is one of the typical immune disorders encountered during the application of dental/medical materials and has a highly complex pathogenic mechanism. Semaphorin 3A (Sema3A), a member of the semaphorin family, is reported to be involved in various immune disorders.
Lipei Liu, Megumi Watanabe, Norikazu Minami, Mohammad Yunizar, Tetsuo Ichikawa   +4 more
openaire   +1 more source

Tumor extracellular vesicles drive metastasis (it's a long way from home)

FASEB BioAdvances, Volume 3, Issue 11, Page 930-943, November 2021., 2021
Abstract Among a plethora of functions, extracellular vesicles released by primary tumors spread in the organism and reach distant organs where they can induce the formation of a premetastatic niche. This constitutes a favorable microenvironment for circulating tumor cells which facilitates their seeding and colonization.
Shima Ghoroghi, Benjamin Mary, Nandini Asokan, Jacky G. Goetz, Vincent Hyenne   +4 more
wiley   +1 more source

The Entry and Egress of Monocytes in Atherosclerosis: A Biochemical and Biomechanical Driven Process

Cardiovascular Therapeutics, Volume 2021, Issue 1, 2021., 2021
In accordance with “the response to injury” theory, the entry of monocytes into the intima guided by inflammation signals, taking up cholesterol and transforming into foam cells, and egress from plaques determines the progression of atherosclerosis. Multiple cytokines and receptors have been reported to be involved in monocyte recruitment such as CCL2 ...
Hongyan Kang, Xinyu Li, Kewen Xiong, Zhiyun Song, Jiaxin Tian, Yuqiao Wen, Anqiang Sun, Xiaoyan Deng, Victor Garcia   +8 more
wiley   +1 more source

Semaphorin3A–neuropilin1 signalling is involved in the generation of cortical interneurons [PDF]

Brain Structure and Function, 2016
Cortical interneurons are generated predominantly in the medial ganglionic eminence of the ventral telencephalon and migrate to the cortex during embryonic development. These cells express neuropilin (Nrp1 and Nrp2) receptors which mediate their response to the chemorepulsive class 3 semaphorin (Sema) ligands.
William D. Andrews, Melissa Barber, Marion Nemitz, Fani Memi, John G. Parnavelas   +4 more
openaire   +3 more sources

PlexinA4-Semaphorin3A mediated crosstalk between main cortical interneuron classes is required for superficial interneurons lamination

, 2021
We demonstrate that the two main classes of interneurons (INs) communicate during cortical development. MGE-derived INs first colonize deep layers and serve as guidepost for later-arriving HTR3A+ INs.
Limoni, G
core   +3 more sources

[Retracted] Shared Genetic and Epigenetic Mechanisms between the Osteogenic Differentiation of Dental Pulp Stem Cells and Bone Marrow Stem Cells

BioMed Research International, Volume 2021, Issue 1, 2021., 2021
Objective. To identify the shared genetic and epigenetic mechanisms between the osteogenic differentiation of dental pulp stem cells (DPSC) and bone marrow stem cells (BMSC). Materials and Methods. The profiling datasets of miRNA expression in the osteogenic differentiation of mesenchymal stem cells from the dental pulp (DPSC) and bone marrow (BMSC ...
Sebastian Gaus, Hanluo Li, Simin Li, Qian Wang, Tina Kottek, Sebastian Hahnel, Xiangqiong Liu, Yupei Deng, Dirk Ziebolz, Rainer Haak, Gerhard Schmalz, Lei Liu, Vuk Savkovic, Bernd Lethaus, Min Tang   +14 more
wiley   +1 more source

Involvement of Fes/Fps tyrosine kinase in semaphorin3A signaling [PDF]

The EMBO Journal, 2002
Collapsin response mediator proteins (CRMPs)/TOAD64/Ulips/DRPs and CRAM have emerged as strong candidates for a role in semaphorin signaling. In this study we identified Fes/Fps (Fes) tyrosine kinase in the CRMP-CRAM complex and investigated whether Fes was involved in semaphorin3A (Sema3A) signaling.
Norihiro, Mitsui, Ryoko, Inatome, Shusuke, Takahashi, Yoshio, Goshima, Hirohei, Yamamura, Shigeru, Yanagi   +5 more
openaire   +2 more sources