Results 51 to 60 of about 910 (176)
Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.Diazirines are three‐membered, nitrogen‐containing heterocycles that decompose under light or heat to generate carbenes. For the past two decades, they have served mainly as minimally invasive tags in photoaffinity labeling (PAL). More recently, their value as versatile carbene precursors has been recognized.
Dominik Schnalzer +4 more
wiley +2 more sources
Frontiers in Immunology, 2019 Semaphorin 3A (sema3A) belongs to the sub-family of the immune semaphorins that function as regulators of immune-mediated inflammation. Sema3A is a membrane associated molecule on T regulatory cells and on B regulatory cells. Being transiently ligated to
Sabag D. Adi +8 more
doaj +1 more source
Exercise training and muscle–lung crosstalk: The emerging roles of Irisin and Semaphorin-3A in pulmonary diseases. A narrative review [PDF]
Journal of Exercise & Organ Cross Talk, 2021 COPD is an inflammatory disorder caused by prolonged inhalation of harmful substances such as cigarette smoke that leads to an irreversible respiratory disorder.
Mostafa Ghanei +4 more
doaj +1 more source
Neuropilin1 silencing impairs the proliferation and migration of cells in pancreatic cancer
Journal of Clinical Laboratory Analysis, Volume 34, Issue 9, September 2020., 2020 Abstract Background Neuropilin1 (NRP1) participates in cancer cell proliferation, migration, and metastasis as a multifunctional co‐receptor by interacting with multiple signal pathways, but few studies have addressed the precise function of NRP1 in pancreatic cancer (PACA) cells.
Li‐Hong He +7 more
wiley +1 more source
Journal of Leukocyte Biology, Volume 108, Issue 3, Page 999-1011, September 2020., 2020 Graphical Abstract EPHB2 expression in monocytes promotes monocyte accumulation by increasing monocyte adhesion and transendothelial migration; subsequently, this can contribute to atherosclerotic plaque progression. Abstract The molecular basis of atherosclerosis is not fully understood and mice studies have shown that Ephrins and EPH receptors play a
Dianne Vreeken +8 more
wiley +1 more source
Prolyl Isomerase Pin1 Regulates Axon Guidance by Stabilizing CRMP2A Selectively in Distal Axons
Cell Reports, 2015 Axon guidance relies on precise translation of extracellular signal gradients into local changes in cytoskeletal dynamics, but the molecular mechanisms regulating dose-dependent responses of growth cones are still poorly understood.
Martin Balastik +15 more
doaj +1 more source
Periosteum Metabolism and Nerve Fiber Positioning Depend on Interactions between Osteoblasts and Peripheral Innervation in Rat Mandible. [PDF]
PLoS ONE, 2015 The sympathetic nervous system controls bone remodeling by regulating bone formation and resorption. How nerves and bone cells influence each other remains elusive.
Cédric Mauprivez +8 more
doaj +1 more source
Semaphorin3A: A potential therapeutic tool in immune-mediated diseases. [PDF]
Eur J Rheumatol, 2018 Abstract The significance of semaphorin3A (sema3A) in regulating immune-mediated inflammation is widely reported. There are multiple mechanisms involved in the process of sema3A-mediated regulation. One of them is the ability of sema3A to maintain a sufficient regulation of both T-cell and B-cell activation.
Vadasz Z, Toubi E.
europepmc +3 more sources
Semaphorin-3A protects against neointimal hyperplasia after vascular injuryResearch in context
EBioMedicine, 2019 Background: Neointimal hyperplasia is a prominent pathological event during in-stent restenosis. Phenotype switching of vascular smooth muscle cells (VSMCs) from a differentiated/contractile to a dedifferentiated/synthetic phenotype, accompanied by ...
Jie-hong Wu +11 more
doaj +1 more source
Egyptian Rheumatology and Rehabilitation, 2020 Background Serum14-3-3η protein plays an important role in the pathogenesis of rheumatoid arthritis (RA) as it is a joint-derived proinflammatory mediator.
Nivine Fathi Darwish +3 more
doaj +1 more source