Results 111 to 120 of about 7,206 (213)
Impact of semaphorin expression on prognostic characteristics in breast cancer
Breast Cancer: Targets and Therapy, 2018 Ramesh Butti, Totakura VS Kumar, Ramakrishna Nimma, Gopal C Kundu Laboratory of Tumor Biology, Angiogenesis and Nanomedicine Research, National Centre for Cell Science, Savitribai Phule Pune University, Pune, India Abstract: Breast cancer is one of the ...
Butti R, Kumar TVS, Nimma R, Kundu GC
doaj
The involvement of immune semaphorins and neuropilin-1 in lupus nephritis
, 2011 Background and objectives: Neuropilin-1 (NP-1), a functional vascular endothelial growth factor (VEGF) receptor, is important in the priming of resting T cells and contributes to the development of peripheral tolerance.
Z Vadasz +6 more
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Nature Communications, 2017 Semaphorins and their receptors are involved in neurodevelopment, but their functions in the adult nervous system are not fully understood. This study finds that semaphorin 4C and its receptor Plexin B are expressed in sensory neurons and are ...
Eszter Paldy +6 more
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Semaphorins in cancer: Biological mechanisms and therapeutic approaches
, 2013 The hallmarks of cancer include multiple alterations in the physiological processes occurring in normal tissues, such as cell proliferation, apoptosis, and restricted cell migration. These aberrant behaviors are due to genetic and epigenetic changes that
Tamagnone, Luca
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Role of class 5 semaphorins in LTD-mediated synapse elimination
, 2016 The semaphorins are a large protein family, highly conserved across diverse phyla. They are expressed throughout the body, with a diversity of functions including axon guidance, synapse development and plasticity, cell proliferation and migration ...
Gomm, Rachel
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Semaphorins in the development, homeostasis and disease of hormone systems.
, 2012 International audienceSemaphorin proteins are among the best-studied families of guidance cues. Initially characterized as repulsive neuronal guidance cues, during the last decade, significant progress has been made in defining their involvement in the ...
Giacobini, Paolo, Prevot, Vincent
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, 1999 In Drosophila, plexin A is a functional receptor for semaphorin-1a. Here we show that the human plexin gene family comprises at least nine members in four subfamilies. Plexin-B1 is a receptor for the transmembrane semaphorin Sema4D (CD100), and plexin-C1
Chen, Hang +11 more
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Editorial: Targeting Angiogenesis to Treat Autoimmune Diseases and Cancer
Frontiers in Immunology, 2020 Michal A. Rahat +5 more
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The functions of Semaphorins in the neural development
During embryogenesis, axons reach their specific targets correctly to form the complex neural network found in the mature functional nervous system.
Masahiko, Taniguchi
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Glia–glia crosstalk via semaphorins: Emerging implications in neurodegeneration
The central nervous system (CNS) is wired by a complex network of integrated glial and neuronal signals, which is critical for its development and homeostasis.
Luca Tamagnone +4 more
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