Results 211 to 220 of about 30,050 (236)

Unraveling the complexity of the senescence-associated secretory phenotype in adamantinomatous craniopharyngioma using multimodal machine learning analysis. [PDF]

Neuro Oncol
Prince EW, Apps JR, Jeang J, Chee K, Medlin S, Jackson EM, Dudley R, Limbrick D, Naftel R, Johnston J, Feldstein N, Prolo LM, Ginn K, Niazi T, Smith A, Kilburn L, Chern J, Leonard J, Lam S, Hersh DS, Gonzalez-Meljem JM, Amani V, Donson AM, Mitra SS, Bandopadhayay P, Martinez-Barbera JP, Hankinson TC.   +26 more
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Resistance training suppresses accumulation of senescent fibro-adipogenic progenitors and senescence-associated secretory phenotype in aging rat skeletal muscle. [PDF]

Geroscience
Hung YL, Sato A, Takino Y, Ishigami A, Machida S.   +4 more
europepmc   +1 more source

Mitochondrial injury induced by a Salmonella genotoxin triggers the proinflammatory senescence-associated secretory phenotype. [PDF]

Nat Commun
Chen HY, Hsieh WC, Liu YC, Li HY, Liu PY, Hsu YT, Hsu SC, Luo AC, Kuo WC, Huang YJ, Liou GG, Lin MY, Ko CJ, Tsai HC, Chang SJ.   +14 more
europepmc   +1 more source

Targeting the senescence-associated secretory phenotype in cancer therapy

, 2023
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Chromatin basis of the senescence-associated secretory phenotype

Trends in Cell Biology, 2022
Cellular senescence is a stable cell growth arrest. Senescent cells are metabolically active, as exemplified by the secretion of inflammatory cytokines, chemokines, and growth factors, which is termed senescence-associated secretory phenotype (SASP).
Xue, Hao, Chen, Wang, Rugang, Zhang
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The senescence-associated secretory phenotype in ovarian cancer dissemination

American Journal of Physiology-Cell Physiology, 2022
Ovarian cancer is a highly aggressive disease with poor survival rates in part due to diagnosis after dissemination throughout the peritoneal cavity. It is well-known that inflammatory signals affect ovarian cancer dissemination. Inflammation is a hallmark of cellular senescence, a stable cell cycle arrest induced by a variety of stimuli including ...
Jacob P. Veenstra, Lucas Felipe Fernandes Bittencourt, Katherine M. Aird   +2 more
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