Results 211 to 220 of about 8,456,945 (252)

Treating age‐related loss of muscle mass and function: Where should we be focusing?

The Journal of Physiology, Volume 604, Issue 17, Page 7059-7075, 1 September 2026.
Abstract figure legend Perturbations contributing to the age‐related loss of muscle mass and strength. A, in the spinal cord, self‐reinforcing cycles of oxidative stress, mitochondrial dysfunction and inflammation mediated by cells, including microglia, contribute to motor neuron degeneration.
Daniel J. Ham, Christopher S. Fry, Avnika Ashok Ruparelia, Shyuan T. Ngo, Séverine Lamon   +4 more
wiley   +1 more source

Magnesium Attenuates Renal Senescence and Fibrosis With Reduced DNA Damage Response and H3K4me3 Enrichment at the p16INK4a Promoter

The FASEB Journal, Volume 40, Issue 16, 31 August 2026.
Magnesium (Mg2+) attenuates renal injury in ischemia–reperfusion and radiation‐induced kidney injury models in association with reduced DNA damage response markers, cellular senescence, inflammation, and fibrosis. Mg2+ treatment is associated with reduced H3K4me3 enrichment at the p16INK4a promoter, attenuation of senescence‐associated pathways, and ...
Makoto Matsubara, Kensuke Sasaki, Shigehiro Doi, Takeshi Ike, Maria Yoshida, Akira Takahashi, Yosuke Osaki, Naoki Ishiuchi, Aiko Okubo, Yujiro Maeoka, Takuto Chiba, Ayumu Nakashima, Takao Masaki   +12 more
wiley   +1 more source

Intracranial aneurysms as a manifestation of premature vascular aging: Cellular senescence, inflammaging, and wall degeneration. [PDF]

Ageing Res Rev
Maeda T, Sato H, Nakano Y, Kobayashi H, Take Y, Nisson PL, Cisneros O, Rahmani R, Jackson B, Castro JC, Tatsumi M, Patel G, Little EL, Jackson H, Lawton MT, Hashimoto T, Sato H.   +16 more
europepmc   +1 more source

Depletion of Senescent Cells and Targeting the Senescence Associated Secretory Phenotype (SASP) Effectively Treats Chronic Rejection

American Journal of Transplantation
Y. Xiao, T. Matsunaga, K. Nakamori, M. Gizlenci, Z. Song, S. Tsou, F. Martin, M. Kayumov, R. Wolff Von Gudenberg, C. Kupsch, H. Zhou, S. Tullius   +11 more
openaire   +1 more source

SASP-mediated cellular senescence following myocardial infarction: from spatiotemporal immune regulation to therapeutic strategies. [PDF]

Front Immunol
Zhang F, Liao Y, Yang P, Guo J.
europepmc   +1 more source

Hepatic Cellular Senescence Is Attenuated by Filbertone via Modulation of the p53-p21 Pathway in AML12 Hepatocytes. [PDF]

Nutrients
Park S, Ahn B.
europepmc   +1 more source

Immunosenescence in prostate cancer: from aging-related immune dysfunction to therapeutic opportunities. [PDF]

Front Immunol
Guo J, Wu K, Ma Z, Guo S, Wang F, Lu L.
europepmc   +1 more source

Mitochondrial regulation of cellular senescence heterogeneity. [PDF]

Front Cell Dev Biol
Ahn M, Yoon SJ, Seo JH.
europepmc   +1 more source

Decellularized Extracellular Matrix Mitigates the Senescent Phenotype and Restores Osteogenic Potential in Human Mesenchymal Stromal Cells. [PDF]

J Orthop Res
Dorais CJ, Kruger NM, Ramos-Rodriguez DH, Lee MA, Kent Leach J.   +4 more
europepmc   +1 more source

Molecular mechanisms and recent advances in cellular senescence. [PDF]

Cell Biosci
Hussain A, Tatar M, Gong R.
europepmc   +1 more source