Results 121 to 130 of about 6,153 (216)

Internship Reports and Monograph “Senolytics and Senomorphics for the Treatment of Osteoarthritis”

, 2021
Relatório de Estágio do Mestrado Integrado em Ciências Farmacêuticas apresentado à Faculdade de FarmáciaRealizado no âmbito da Unidade Curricular “Estágio Curricular” do Mestrado Integrado em Ciências Farmacêuticas da Faculdade de Farmácia da ...
Paz, Mariana Domingues
core  

Paradoxes of senolytics

Aging, 2018
openaire   +2 more sources

Senolytic CAR T cells [PDF]

Nature Medicine, 2020
openaire   +2 more sources

clinical translation: senolytics and anti-aging

This study investigates the current state of clinical translation pathways for senolytic therapeutics in anti-aging interventions, with a focus on identifying translational bottlenecks and advancing evidence-based implementation strategies. As senolytics—
Hok San Chau, Hankun Su
core   +1 more source

Senescent immune cells, inflammaging, and bone loss: therapeutic potential and translational challenges of senolytics in osteoporosis. [PDF]

Front Endocrinol (Lausanne)
Zhu M, Zhang J, Fang H, Cai K, Wu Q, Gao C, Wang Y, Chen J.   +7 more
europepmc   +1 more source

Targeting cellular senescence in dermatology: senolytic and senomorphic strategies. [PDF]

Geroscience
Haykal D, Flament F, Garibyan L, Lee K, Escot J, Gueniche A, Kirkland J.   +6 more
europepmc   +1 more source

At the Nexus Between Epigenetics and Senescence: The Effects of Senolytic (BI01) Administration on DNA Methylation Clock Age and the Methylome in Aged and Regenerated Skeletal Muscle

Senescent cells emerge with aging and injury. The contribution of senescent cells to DNA methylation age (DNAmAGE) in vivo is uncertain. Furthermore, stem cell therapy can mediate “rejuvenation”, but how tissue regeneration controlled by resident stem ...
Filareto, Antonio, Murach, Kevin A., Sini, Patrizia, Milčiūtė, Milda, Horvath, Steve, Gordevičius, Juozas, Greene, Nicholas P., Brooke, Robert T., Franti, Michael, Wells, Jaden, Malik, Zain B., Wen, Yuan, Dungan, Cory M., Morena, Francielly, Koopmans, Pieter Jan, Weinstabl, Harald, Chambers, Toby L.   +16 more
core   +1 more source

Senolytics Reverse PM_2.5 - Induced Cell and Vascular Dysfunction. [PDF]

Cardiovasc Toxicol
Gomes D, McFall SA, Chen N, Zhao J, Srivastava S, Conklin DJ, O'Toole TE.   +6 more
europepmc   +1 more source

Moving senolytics closer to the clinic in IPF

eBioMedicine, 2023
Daniel Kramer, Gautam George, Ross Summer   +2 more
openaire   +3 more sources

A Review of Rejuvenation Strategies Targeting Mesenchymal Stem Cell Senescence and Their Impact on Bone Health and Regeneration. [PDF]

Curr Osteoporos Rep
Heinrichs DP, Samsonraj RM.
europepmc   +1 more source