Results 101 to 110 of about 728 (163)

Targeting p21 for diabetes: Another choice of senotherapy

Targeting p21 for diabetes: Another choice of senotherapy
Senotherapy, the elimination of senescent cells, is a cutting-edge treatment for aging-related and lifestyle diseases. In this issue of Cell Metabolism, Wang et al. report that p21[Cip1] highly expressing cells, which represent a senescent cell population, occur in the adipose tissue during obesity.
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Editorial: Experimental and computational methods in the development of diagnostics and therapeutics for colon cancer. [PDF]

Front Mol Biosci
Suleman M, Ali S, Rashid F, Khan FI.
europepmc   +1 more source

Is "cellular senescence" a misnomer? [PDF]

Geroscience, 2022
Gems D, Kern CC.
europepmc   +1 more source

Cabozantinib, an Anti-Aging Agent, Prevents Bone Loss in Estrogen-Deficient Mice by Suppressing Senescence-Associated Secretory Phenotype Factors. [PDF]

Int J Mol Sci
Lee J, Oh J, Kim JR, Ha H, Kim T, Jeong D.   +5 more
europepmc   +1 more source

The Role of Renal Cell Senescence in Diabetic Kidney Disease: Mechanisms and Therapeutic Advances. [PDF]

Diabetes Metab Syndr Obes
Yan Z, Xu J, Liu T, Wang L, Zhang Q, Li X, Lin B, Piao C.   +7 more
europepmc   +1 more source

Senolytic Vaccines from the Central and Peripheral Tolerance Perspective. [PDF]

Vaccines (Basel)
Vasilieva MI, Shatalova RO, Matveeva KS, Shindyapin VV, Minskaia E, Ivanov RA, Shevyrev DV.   +6 more
europepmc   +1 more source

β-galactosidase-targeted senolytic prodrug ameliorates preclinical models of post-traumatic osteoarthritis. [PDF]

EBioMedicine
Li Q, Wu T, Fan Y, Cheng J, Wang J, Xu B, Sun M, Gong X, Deng H, Ao Y, Hu X.   +10 more
europepmc   +1 more source

Prodrug nanoplatform for triggering ferroptosis to eliminate senescent cells in age-associated pathologies. [PDF]

Nat Commun
Jin C, Xu X, Yao N, Zhang H, Chen C, Zeng L, Liu Z, Lei L, Cui S, Wen C, Shi L.   +10 more
europepmc   +1 more source

Therapy-Induced Senescence: Novel Approaches for Markers Identification. [PDF]

Int J Mol Sci
Pacifico F, Magni F, Leonardi A, Crescenzi E.   +3 more
europepmc   +1 more source

Advances in Nanotherapy for Targeting Senescent Cells. [PDF]

Int J Nanomedicine
Shi Y, Zhang Y, Zhang Y, Yao J, Guo J, Xu X, Wang L.   +6 more
europepmc   +1 more source