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Biochemical Society Transactions
Cellular senescence, a form of terminal cell cycle arrest, is as a key driver of organismal ageing and an important factor in age-related diseases. Insights into the senescent phenotype have led to the development of novel therapeutic strategies, collectively known as senotherapies, that aim to ameliorate the detrimental effects of senescent cell ...
Vinesh Dhokia +4 more
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Cellular senescence, a form of terminal cell cycle arrest, is as a key driver of organismal ageing and an important factor in age-related diseases. Insights into the senescent phenotype have led to the development of novel therapeutic strategies, collectively known as senotherapies, that aim to ameliorate the detrimental effects of senescent cell ...
Vinesh Dhokia +4 more
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Lineage-guided senescence insights unlock precision senotherapy
Aging ResearchZiqi Kang +3 more
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Senotherapy as a Novel Therapeutic Method in Cancer Treatment: With a Focus on Head and Neck Cancer
Interdisciplinary cancer research, 2023exaly
El papel patológico de las células senescentes está bien establecido en una variedad de enfermedades. A pesar de la amplia evidencia sobre el papel central que las mitocondrias desempeñan en la senescencia celular, la comprensión de las adaptaciones en las mitocondrias de las células senescentes es bastante superficial.
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Proteolysis targeting chimeras as senolytics: An emerging senotherapy for combating aging
The Journal of Pharmacology and Experimental TherapeuticsAlexis B. Cruickshank-Taylor +4 more
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