Self Purification of Two Serine Endopeptidases [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 1972 We have reported that a serine protease from Pronase, homologous with bovine chymotrypsin, is both active and stable in 6 M guanidinium chloride. The present investigation examined the possibility that this unique property might be used to permit the ...
William M. Awad +2 more
core +3 more sources
Characterization of endopeptidases from the midgut of Morimus funereus (Coleoptera: Cerambycidae) larvae [PDF]
Archives of Biological Sciences, 2008 Application of specific chromogenic substrates, use of class-specific inhibitors, and zymogram analysis enabled us to identify several peptidase classes in extracts of the midgut of Morimus funereus larvae.
Božić Nataša +5 more
doaj +5 more sources
Characterisation of proteins in excretory/secretory products collected from salmon lice, Lepeophtheirus salmonis [PDF]
Parasites & Vectors, 2018 Background The salmon louse, Lepeophtheirus salmonis, is an ectoparasitic copepod which feeds on the mucus, skin and blood of salmonid fish species. The parasite can persist on the surface of the fish without any effective control being exerted by the ...
Scott Hamilton +12 more
doaj +5 more sources
Phosphorylated acidic serine–aspartate-rich MEPE-associated motif peptide from matrix extracellular phosphoglycoprotein inhibits phosphate regulating gene with homologies to endopeptidases on the X-chromosome enzyme activity [PDF]
Journal of Endocrinology, 2007 Inactivating PHEX (phosphate regulating gene with homologies to endopeptidases on the X chromosome) mutations cause X-linked hypophosphatemia in humans and mice (Hyp) through overproduction of fibroblast growth factor 23 (FGF23) a phosphaturic factor, by
Shiguang Liu +4 more
openalex +2 more sources
Novel features of serine protease active sites and specificity pockets: sequence analysis and modelling studies of glutamate-specific endopeptidases and epidermolytic toxins [PDF]
Protein Engineering, 1996 With a view to obtaining a better understanding of the structural determinants of P1 glutamate specificity in glutamate-specific endopeptidases (GSEs), the active sites and specificity pockets of such enzymes from Bacillus licheniformis (gse-bl ...
João Alexandra +3 more
openalex +2 more sources
Insights into the efficient degradation mechanism of extracellular proteases mediated by Purpureocillium lilacinum [PDF]
Frontiers in MicrobiologyProtease secretion is crucial for degrading nematode cuticles using nematophagous fungus Purpureocillium lilacinum, but the secretion pattern of protease remains poorly understood.
Xiujun Zhang +7 more
doaj +2 more sources
The structure of the Gemella haemolysans M26 IgA1 protease trypsin-like domain. [PDF]
Acta Crystallogr F Struct Biol CommunThe 1.75 Å resolution structure of the G. haemolysans M26 IgA1 protease trypsin‐like domain is presented. The structural data suggest that the domain exists in an inactive pro‐enzyme‐like state when in the context of the full‐length protein. This putative pro‐enzyme may be activated after being N‐terminally excised from the larger M26 enzyme structure ...
Tran N +3 more
europepmc +2 more sources
Homologous inhibitors from potato tubers of serine endopeptidases and metallocarboxypeptidases.
Proceedings of the National Academy of Sciences of the United States of America, 1976 A potent polypeptide inhibitor of chymotrypsin has been purified from Russett Burbank potatoes. The inhibitor has no effect on bovine carboxypeptidases A or B but exhibits homology with a carboxypeptidase inhibitor that is also present in potato tubers ...
Claus HASS +2 more
openalex +2 more sources
Frontiers in Immunology, 2023 Glioblastoma is the most common primary malignant tumor of the central nervous system, which has the characteristics of strong invasion, frequent recurrence, and rapid progression.
Hao Liu +19 more
doaj +2 more sources
Modeling and structural analysis of PA clan serine proteases
BMC Research Notes, 2012 Background Serine proteases account for over a third of all known proteolytic enzymes; they are involved in a variety of physiological processes and are classified into clans sharing structural homology. The PA clan of endopeptidases is the most abundant
Laskar Aparna +3 more
doaj +2 more sources