Results 71 to 80 of about 185,677 (239)
ChemMedChem, EarlyView.Dysregulated proteolysis mediated by kallikrein‐related peptidases (KLKs) and iron overload are involved in the progression of neurodegenerative diseases. Deferasirox, an clinically‐approved iron chelator, and its newly synthesized derivatives have been identified as inhibitors of major central nervous system KLKs with low cytotoxicity and effective ...
Rilès Boumali +11 more
wiley +1 more source
A biotechnology perspective of fungal proteases [PDF]
, 2015 Proteases hydrolyze the peptide bonds of proteins into peptides and amino acids, being found in all living organisms, and are essential for cell growth and differentiation.
Almeida, Renata Paula Coppini de +9 more
core +1 more source
Effect of Natural Polyphenols on Breast Cancer Chemoprevention and Treatment
Molecular Nutrition &Food Research, EarlyView.Effect of Natural Polyphenols on Breast Cancer proliferation and progression. ABSTRACT Breast cancer is the most common type of malignancy among women worldwide. Significant achievements have been made in diagnostic tools and cancer treatments in the past decade; however, the complexity and heterogeneity of certain breast cancer subtypes often lead to ...
Marzia Sichetti +4 more
wiley +1 more source
Search for novel proteolytic enzymes aimed at textile and agro-industrial applications: an overview of current and novel approaches [PDF]
, 2012 The types and sources of proteolytic enzymes, enzyme assays, strategies for fermentation yield improvement, and novel proteases and their applications in industrial sectors are widely covered in this review.
Malcata, F. Xavier +2 more
core +1 more source
Tsetse fly (Glossina pallidipes) midgut responses to Trypanosoma brucei challenge
Parasites & Vectors, 2017 Background Tsetse flies (Glossina spp.) are the prominent vector of African trypanosome parasites (Trypanosoma spp.) in sub-Saharan Africa, and Glossina pallidipes is the most widely distributed species in Kenya.
Rosemary Bateta +7 more
doaj +1 more source
Production and Characterisation of Thermostable Protease from Bacillus Stearothermophilus Strain F1 [PDF]
, 1994 Screening and isolation of thermophilic proteolytic bacteria were carried out from composting areas, high temperature ponding systems and areas surrounding palm oil mills.
Raja Abd. Rahman, Raja Noor Zaliha
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Identification of a novel 82 kDa proMMP-9 species associated with the surface of leukaemic cells [PDF]
, 2007 MMP-9 (matrix metalloproteinase 9) plays a critical role in tumour progression. Although the biochemical properties of the secreted form of proMMP-9 are well characterized, little is known about the function and activity of cell surface-associated proMMP-
Egea, Virginia +6 more
core +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2005 Prolyl endopeptidases (PEPs) are a unique class of serine proteases with considerable therapeutic potential for the treatment of celiac sprue. The crystal structures of two didomain PEPs have been solved in alternative configurations, thereby providing ...
L. Shan, I. Mathews, C. Khosla
semanticscholar +1 more source
British Journal of Pharmacology, EarlyView.Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
wiley +1 more source
Enzymatic hydrolysis of vegetable and insect proteins using technical enzyme preparations [PDF]
, 2021 The present dissertation covers the usage of technical enzyme preparations (TEPs) for vegetable and insect protein hydrolysis, due to the mounting interest in alternative protein sources to cover the increasing demand for food from a growing world ...
Großmann, Kora Kassandra
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