Results 111 to 120 of about 118,022 (186)

Forebrain expression of serine racemase during postnatal development. [PDF]

Neurochem Int, 2021
Folorunso OO, Harvey TL, Brown SE, Cruz C, Shahbo E, Ajjawi I, Balu DT.   +6 more
europepmc   +1 more source

Human Serine Racemase Weakly Binds the Third PDZ Domain of PSD-95. [PDF]

Int J Mol Sci, 2022
Giaccari R, Marchesani F, Compari C, Fisicaro E, Mozzarelli A, Campanini B, Bettati S, Bruno S, Faggiano S.   +8 more
europepmc   +1 more source

Viral vector-mediated upregulation of serine racemase expression in medial prefrontal cortex improves learning and synaptic function in middle age rats. [PDF]

Aging (Albany NY), 2023
Yegla B, Rani A, Kumar A.
europepmc   +1 more source

A New Three-Hit Mouse Model of Neurodevelopmental Disorder with Cognitive Impairments and Persistent Sociability Deficits

Brain Sciences
Background/Objectives: Cognitive deficits and negative symptoms associated with schizophrenia are poorly managed by current antipsychotics. In order to develop effective treatments, refining animal models of neurodevelopmental disorders is essential ...
Imane Mouffok, Caroline Lahogue, Thomas Cailly, Thomas Freret, Valentine Bouet, Michel Boulouard   +5 more
doaj   +1 more source

Is serine racemase (SRR) a second hit target for LRRK2-G2019S induced Parkinson's disease? [PDF]

Neural Regen Res, 2021
Nickels SL, Schwamborn JC.
europepmc   +1 more source

Factors regulating serine racemase and d-amino acid oxidase expression in the mouse striatum. [PDF]

Brain Res, 2021
Takagi S, Balu DT, Coyle JT.
europepmc   +1 more source

Cloning and expression of a serine racemase gene homologue of the green alga Chlamydomonas reinhardtii and characterization of the gene product [PDF]

, 2019
A unicellular green alga Chlamydomonas reinhardtii (C. reinhardtii) has served as a model system to study many fundamental biological processes. We demonstrated that some D-amino acids have no inhibitory effect on the growth of C.
tanigawa, Minoru, nishimura, Katsushi n, Koike, Miya   +2 more
core  

Cyclopropane derivatives as potential human serine racemase inhibitors: unveiling novel insights into a difficult target

, 2018
d-Serine is the co-agonist of NMDA receptors and binds to the so-called glycine site. d-Serine is synthesized by human serine racemase (SR). Over activation of NMDA receptors is involved in many neurodegenerative diseases and, therefore, the inhibition ...
Chiara Cocconcelli (2627434), Andrea Mozzarelli (68231), Gabriele Costantino (147913), Marco Pieroni (1550053), Marialaura Marchetti (2627431), Claudia Beato (1870750), Barbara Campanini (475262), Chiara Pecchini (2627437)   +7 more
core   +1 more source

Commentary on Urinary l-erythro-β-hydroxyasparagine: a novel serine racemase inhibitor and substrate of the Zn2+-dependent d-serine dehydratase. [PDF]

Biosci Rep, 2021
Tamaki FK.
europepmc   +1 more source

Characterization of recombinant human serine racemase

, 2010
6 Brief Abstract The pyridoxal-5'-phosphate-dependent enzyme serine racemase (SR) is responsible for the biosynthesis of D-serine in the mammalian central nervous system.
Hoffman, Hillary Elizabeth
core   +1 more source