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How Shelterin Orchestrates the Replication and Protection of Telomeres

Cold Spring Harbor Perspectives in Biology
Efforts to determine how telomeres solve the end-protection problem led to the discovery of shelterin, a conserved six-subunit protein complex that specifically binds to the long arrays of telomeric TTAGGG repeats at vertebrate chromosome ends. The mechanisms by which shelterin prevents telomeres from being detected as sites of DNA damage and how ...
openaire   +2 more sources

Expression of shelterin and shelterin-associated genes in breast cancer cell lines

2014
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.
openaire   +1 more source

Shelterin' the Ends

Science, 2009
openaire   +1 more source

Shelterin the Ends

Science, 2010
openaire   +1 more source

Knockout of Shelterin subunit genes in zebrafish results in distinct outcomes

Biochemical and Biophysical Research Communications, 2022
Jinmin Ma, Ruilin Zhang
exaly  

The structural biology of the shelterin complex

Biological Chemistry, 2019
Yong Chen
exaly  

Targeting the telomere and shelterin complex for cancer therapy: current views and future perspectives

Journal of Cellular and Molecular Medicine, 2011
Alan E Bilsland   +2 more
exaly  

Quantitative Biology of Human Shelterin and Telomerase: Searching for the Weakest Point

International Journal of Molecular Sciences, 2019
Tomáš Janovic, Ctirad Hofr
exaly  

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