Results 31 to 40 of about 9,573 (184)
Pathway-based screening strategy for multitarget inhibitors of diverse proteins in metabolic pathways. [PDF]
PLoS Computational Biology, 2013 Many virtual screening methods have been developed for identifying single-target inhibitors based on the strategy of "one-disease, one-target, one-drug".
Kai-Cheng Hsu +4 more
doaj +1 more source
Characteristics of the tomato chromoplast revealed by proteomic analysis [PDF]
, 2010 Chromoplasts are non-photosynthetic specialized plastids that are important in ripening tomato fruit (Solanum lycopersicum) since, among other functions, they are the site of accumulation of coloured compounds.
Barsan, Cristina +9 more
core +7 more sources
Journal of Integrative Agriculture, 2021 Glyphosate inhibits the enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) and overexpression of the EPSPS gene is one of the molecular mechanisms conferring glyphosate resistance in weeds.
Chun ZHANG +4 more
doaj +1 more source
Organellar carbon metabolism is co-ordinated with distinct developmental phases of secondary xylem [PDF]
, 2019 Subcellular compartmentation of plant biosynthetic pathways in the mitochondria and plastids requires coordinated regulation of nuclear encoded genes, and the role of these genes has been largely ignored by wood researchers. In this study, we constructed
Fierro Gutierrez, Ana Carolina Elisa +4 more
core +2 more sources
PLoS ONE, 2022 Larrea tridentata (Sesse and Moc. ex DC.) Coville (family: Zygophyllaceae) is an aromatic evergreen shrub with resin-covered leaves, known to use in traditional medicine for diverse ailments.
Mohammad Ajmal Ali +6 more
doaj +2 more sources
Shikimate Kinase Isoenzymes in Salmonella typhimurium
Journal of Biological Chemistry, 1968 Abstract A study was undertaken of the shikimate kinase activity of extracts of Salmonella typhimurium. Chromatography on diethylaminoethyl cellulose revealed consistently the presence of two widely separated peaks of activity, the faster moving enzyme being more unstable than the slower moving, major enzymic constituent.
H, Morell, D B, Sprinson
openaire +2 more sources
Molecular phenotyping of the pal1 and pal2 mutants of Arabidopsis thaliana reveals far-reaching consequences on phenylpropanoid, amino acid, and carbohydrate metabolism [PDF]
, 2004 The first enzyme of the phenylpropanoid pathway, Phe ammonia-lyase (PAL), is encoded by four genes in Arabidopsis thaliana. Whereas PAL function is well established in various plants, an insight into the functional significance of individual gene family ...
Boerjan, Wout +13 more
core +3 more sources
Shikimate binding in Helicobacter pylori Shikimate Kinase
The FASEB Journal, 2006 Shikimate kinase (EC 2.7.1.71) catalyzes the specific phosphorylation of the 3‐hydroxyl group of shikimic acid in the presence of ATP. As the fifth key step in shikimate pathway for aromatic amino acid biosynthesis in bacteria, fungi, and plants, but not mammals, shikimate kinase represents an attractive target for the development ...
Wen‐Chi Cheng +3 more
openaire +1 more source
Metabolic and molecular events occurring during chromoplast biogenesis [PDF]
, 2011 Chromoplasts are nonphotosynthetic plastids that accumulate carotenoids. They derive from other plastid forms, mostly chloroplasts. The biochemical events responsible for the interconversion of one plastid form into another are poorly documented. However,
Barsan, Cristina +8 more
core +2 more sources
Frontiers in Bioengineering and Biotechnology, 2022 2-Phenylethanol (2-PE) is a rose-scented aromatic compound, with broad application in cosmetic, pharmaceutical, food and beverage industries. Many plants naturally synthesize 2-PE via Shikimate Pathway, but its extraction is expensive and low-yielding ...
Giulia Usai +11 more
doaj +1 more source