Toward eradication of B-vitamin deficiencies : considerations for crop biofortification [PDF]
, 2018 'Hidden hunger' involves insufficient intake of micronutrients and is estimated to affect over two billion people on a global scale. Malnutrition of vitamins and minerals is known to cause an alarming number of casualties, even in the developed world ...
Strobbe, Simon +1 more
core +3 more sources
Shikimate Kinase from Spinach Chloroplasts [PDF]
Plant Physiology, 1990 Shikimate kinase was purified to near homogenity from spinach Spinacia oleracea L. chloroplasts and found to consist of a single 31 kilodalton polypeptide. The purified enzyme was unstable, but could be stabilized by a variety of added proteins, including oxidized and reduced thioredoxins. Whereas the isolated enzyme was stimulated by mono- and dithiol
C L, Schmidt +3 more
openaire +2 more sources
New Isozyme Systems for Maize (Zea mays L.): Aconitate Hydratase, Adenylate Kinase, NADH Dehydrogenase, and Shikimate Dehydrogenase [PDF]
, 1988 Electrophoretic variation and inheritance of four novel enzyme systems were studied in maize (Zea mays L.). A minimum of 10 genetic loci collectively encodes isozymes of aconitate hydratase (ACO; EC 4.2.1.3.), adenylate kinase (ADK; EC 2.7.4.3), NADH ...
Beckett, J. B. +4 more
core +3 more sources
Metabolic engineering for the production of shikimic acid in an evolved Escherichia coli strain lacking the phosphoenolpyruvate: carbohydrate phosphotransferase system [PDF]
, 2010 Background Shikimic acid (SA) is utilized in the synthesis of oseltamivir-phosphate, an anti-influenza drug. In this work, metabolic engineering approaches were employed to produce SA in Escherichia coli strains derived from an evolved strain (PB12 ...
Adelfo Escalante +7 more
core +1 more source
Global genome analysis of the shikimic acid pathway reveals greater gene loss in host-associated than in free-living bacteria [PDF]
, 2010 Background A central tenet in biochemistry for over 50 years has held that microorganisms, plants and, more recently, certain apicomplexan parasites synthesize essential aromatic compounds via elaboration of a complete shikimic acid pathway ...
Bijal Amin +10 more
core +2 more sources
Pleiotropic and Epistatic Network-Based Discovery: Integrated Networks for Target Gene Discovery [PDF]
, 2018 Biological organisms are complex systems that are composed of functional networks of interacting molecules and macro-molecules. Complex phenotypes are the result of orchestrated, hierarchical, heterogeneous collections of expressed genomic variants ...
DiFazio, Stephen +14 more
core +3 more sources
Frontiers in Microbiology, 2022 Rhizoctonia solani has a broad host range and results in significant losses in agricultural production. Here, an integrated transcriptomic analysis was performed to reveal the critical genes responsible for the pathogenesis of R.
Xinchun Li +8 more
doaj +1 more source
The acanthamoeba shikimate pathway has a unique molecular arrangement and is essential for aromatic amino acid biosynthesis [PDF]
, 2015 The shikimate pathway is the only known biosynthetic route for de novo synthesis of aromatic compounds. It is described as an ancient eukaryotic innovation that has been retained in a subset of eukaryotes, replaced in plants through the acquisition of ...
Campbell, Sara J. +5 more
core +1 more source
BMC Biotechnology, 2020 Background Pelargonium sidoides is an important traditional medicine in South Africa with a well-defined history of both traditional and documented use of an aqueous-ethanolic formulation of the roots of P.
V. Lukman +7 more
doaj +1 more source
Biosynthesis of α-Tocopherol and Plastoquinone-9 in spinach chloroplasts [PDF]
, 1980 Prenylation and methylation reaction in al biosynthesis is localized in the envelope membranes of the chloroplasts, while PQ-9 biosynthesis takes place in the envelope membranes and also in the thylakoid membranes.
Mazliak, P. +2 more
core +1 more source