Helicobacter pylori infection is a WHO class 1 carcinogenic factor of gastric adenocarcinoma. In the past decades, many studies have demonstrated the increasing trend of antibiotic resistance and pointed out the necessity of new effective treatment. This
Pedro Fong +4 more
doaj +1 more source
Mutation of the inducible ARABIDOPSIS THALIANA CYTOCHROME P450 REDUCTASE2 alters lignin composition and improves saccharification [PDF]
ARABIDOPSIS THALIANA CYTOCHROME P450 REDUCTASE1 (ATR1) and ATR2 provide electrons from NADPH to a large number of CYTOCHROME P450 (CYP450) enzymes in Arabidopsis (Arabidopsis thaliana).
Boerjan, Wout +7 more
core +2 more sources
Identification of a missing link in the evolution of an enzyme into a transcriptional regulator. [PDF]
The evolution of transcriptional regulators through the recruitment of DNA-binding domains by enzymes is a widely held notion. However, few experimental approaches have directly addressed this hypothesis.
Gonzalo Durante-Rodríguez +6 more
doaj +1 more source
Bipolaris maydis is pathogen of maize which causes maydis leaf blight disease. In India major losses occur due to the B. maydis race “O” pathogen, whereas in other parts of the world, major losses are due to the race “T” pathogen.
Shweta Meshram +5 more
doaj +1 more source
Tocopherol and plastoquinone synthesis in spinach chloroplasts subfractions [PDF]
Subfractions isolated from intact purified spinach chloroplasts are able to prenylate the aromatic moiety of -tocopherol and plastoquinone-9 precursors. The biosynthesis of -tocopherol and plastoquinone-9 is a compartmentalized process.
Bickel +21 more
core +1 more source
Harnessing Free Radical Scavenging Potential of Caffeic Acid as a Nutraceutical—A Review
Caffeic acid has emerged as a promising bioactive molecule with multiple pharmacological properties, including antioxidant, antimicrobial, anti‐inflammatory, organ protective properties and metal‐chelating ability. This review emphasizes the dietary sources, structural characteristic, molecular mechanism underlying health promoting effects of caffeic ...
Pavitra Behra +2 more
wiley +1 more source
Regulation of Drought and Salt Tolerance by OsSKL2 and OsASR1 in Rice
Abiotic stresses such as salinity and drought greatly impact the growth and production of crops worldwide. Here, a shikimate kinase-like 2 (SKL2) gene was cloned from rice and characterized for its regulatory function in salinity and drought tolerance ...
Yingli Jiang +6 more
doaj +1 more source
A multifaceted approach to identify non-specific enzyme inhibition:Application to Mycobacterium tuberculosis shikimate kinase [PDF]
Single dose high-throughput screening (HTS) followed by dose-response evaluations is a common strategy for the identification of initial hits for further development.
Alturki, Mansour S. +6 more
core +2 more sources
Dextran sodium sulfate confounds causal role of periodontitis in inflammatory bowel disease
Abstract Background Emerging evidence supports a bidirectional link between periodontitis and inflammatory bowel disease (IBD). To investigate this relationship, experimental models commonly use dextran sodium sulfate (DSS) to induce colitis. However, DSS is presumed to selectively affect the colon, and its potential off‐target effects on the oral ...
Himanshi Tanwar +11 more
wiley +1 more source
Effects of glyphosate on isolated maize mitochondria [PDF]
The effects of the herbicide glyphosate (K+ salt) on isolated maize mitochondria have been investigated. Protein synthesis, oxygen uptake (state 3 and state 4 respiration) and passive swelling were inhibited at concentrations in the 10−6–10−2 M range. No
Delibes Castro, Angeles +2 more
core +2 more sources

