Results 51 to 60 of about 5,135,061 (391)
Human adenovirus type 26 uses sialic acid–bearing glycans as a primary cell entry receptor
Science Advances, 2019 Human adenovirus type 26 uses sialic acid as a primary cellular receptor—structural insights for this phase 3 vaccine vector. Adenoviruses are clinically important agents.
A. T. Baker +4 more
semanticscholar +1 more source
Constrained sialic acid donors enable selective synthesis of α-glycosides
Science, 2019 Sweet spot for making oligosaccharides Sugars pose a challenge for chemists: how to string together functional group–rich building blocks that can adopt multiple conformations.
N. Komura +8 more
semanticscholar +1 more source
The Effect of Sialic Acid on MiR-320a and Let-7e Expression in Human Glial Cell Line
Basic and Clinical Neuroscience, 2022 Introduction: Sialic acid is pivotal in various critical physiological events at molecular and cellular levels and pathological processes. Changes in sialic acid concentration are observed in many pathological processes; for example, some available data ...
Negar Noorbakhsh +2 more
doaj
N-acetylneuraminic acid: A scrutinizing tool in oral squamous cell carcinoma diagnosis
Dental Research Journal, 2017 Background: Oral cancer has one of the highest mortality rate among other malignancies. An attempt has been made to assess the genetic expression of a cell surface glycoprotein component - sialic acid released by the malignant cells which will reflect on
Suganya Rajaram +4 more
doaj +1 more source
Frontiers in Molecular Biosciences, 2021 All cells are decorated with a highly dense and complex structure of glycan chains, which are mostly attached to proteins and lipids. In this context, sialic acids are a family of nine-carbon acidic monosaccharides typically found at the terminal ...
Cátia Oliveira Soares +9 more
doaj +1 more source
Sialic acid derivatization for glycan analysis by mass spectrometry
Proceedings of the Japan Academy. Series B, Physical and biological sciences, 2019 Mass spectrometry (MS) is a well-accepted means for analyzing glycans. Before glycan analysis by MS, several chemical derivatizations are generally carried out.
Takashi Nishikaze
semanticscholar +1 more source
Implication of Sialidases in Salmonella Infection: Genome Release of Sialidase Knockout Strains from Salmonella enterica Serovar Typhimurium LT2. [PDF]
, 2017 Sialidases, which are widely distributed in nature, cleave the α-ketosidic bond of terminal sialic acid residue. These emerging virulence factors degrade the host glycan.
Arabyan, Narine +3 more
core +2 more sources
Complement receptor 1 is a sialic acid-independent erythrocyte receptor of Plasmodium falciparum. [PDF]
PLoS Pathogens, 2010 Plasmodium falciparum is a highly lethal malaria parasite of humans. A major portion of its life cycle is dedicated to invading and multiplying inside erythrocytes. The molecular mechanisms of erythrocyte invasion are incompletely understood.
Carmenza Spadafora +7 more
doaj +1 more source
Journal for ImmunoTherapy of Cancer, 2023 Background Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers. Despite the successful application of immune checkpoint blockade in a range of human cancers, immunotherapy in PDAC remains unsuccessful.
Manfred Wuhrer +16 more
doaj +1 more source
Glycomic analysis of high density lipoprotein shows a highly sialylated particle. [PDF]
, 2014 Many of the functional proteins and lipids in high density lipoprotein (HDL) particles are potentially glycosylated, yet very little is known about the glycoconjugates of HDL.
German, J Bruce +6 more
core +1 more source