Results 111 to 120 of about 4,367 (168)

Glycosylated extracellular matrix drives immune suppression by modulating macrophage-T cell crosstalk in triple-negative breast cancer. [PDF]

Nat Commun
Tarantola L, Tyler EJ, Liu Y, Maniati E, Thornton KA, Martín-Otal C, Hanna D, Kumar R, Gauthier V, Hirani P, Burger Ramos M, Roth NJ, Bragg J, Puttock EH, McDermott J, Rajeeve V, Cutillas P, Maiques O, Soulier A, Correa de Sampaio P, Jones LJ, Davies DM, Maher J, Haslam SM, Läubli H, Pearce OMT.   +25 more
europepmc   +1 more source

Unraveling the glyco-immunity nexus in pancreatic cancer. [PDF]

Mol Cancer
Rajesh C, Cummings RD, Radhakrishnan P.
europepmc   +1 more source

Current and evolving practices of carbohydrate antigens in gastric cancer: a narrative review. [PDF]

Transl Cancer Res
Zhao S, Li K, Wang H, Ding Y, Li D.
europepmc   +1 more source

Hypofucosylation promotes pertussis toxin binding to cell surface glycococonjugates and pertussis toxin-induced intracellular ERK signaling. [PDF]

Glycobiology
Konada RSR, Nischan N, Silva A, Kohler JJ.   +3 more
europepmc   +1 more source

Optimizing the preparation of labeled N-glycans for rapid, simplified, and high-precision analysis. [PDF]

PLoS One
Makino R, Natsuka S.
europepmc   +1 more source

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Sialyl-Lewis x and Sialyl-Lewis a are associated with MUC1 in human endometrium

Glycoconjugate Journal, 1996
Endometrial epithelial cells express MUC1 with increased abundance in the secretory phase of the menstrual cycle, when embryo implantation occurs. MUC1 is associated with the apical surface of epithelial cells and is also secreted, being detectable in uterine fluid at elevated levels in the implantation phase.
Hey, Neil A., Aplin, John D.; id_orcid 0000-0001-8777-9261   +1 more
openaire   +3 more sources

Synthesis of Sialyl Lewis X Analogues

Journal of Carbohydrate Chemistry, 1996
Sialyl Lewis X (SLe) analogs 2a and 2b were synthesised, where the N-acetyl-D-glucose and the D-galactose units of SLe 1 were replaced with an alkyl and a heteroalkyl spacer. Sulphate ester 6i was also synthesised from alcohol 6b and chlorosulphonic acid.
Dekany, Gyula, Wright, Karen, Ward, Peter, Toth, Istvan   +3 more
openaire   +2 more sources

Chemoenzymatic Synthesis of Sialyl-Trimeric-Lewis X

Chemistry – A European Journal, 2000
The decasaccharide sialyl-trimeric-Lewis x is a component of glycoproteins and glycolipids that serve as E- and P-selectin ligands. The synthesis of this target structure was accomplished by utilizing a combination of chemical and enzymatic methods.
K M, Koeller, C H, Wong
openaire   +2 more sources

Synthesis of Sialyl Lewis x Analogues 2

Journal of Carbohydrate Chemistry, 1997
Sialyl Lewis X (SLe analogues) containing ß-L-fucopyranosyl residues with an alkyl [-(CH)-] (1a), a heteroalkyl [-(CH)-O-(CH)-] (1b) or a heterocycloalkyl [-2-cyclohexyl-O-(CH)-] (2a) moiety were synthesised by silver ion promoted glycosylation. Further analogues where sialic acid was replaced by a second ß-L-fucopyranosyl (3a, 3b) or hydrogensulphate ...
Dekany, Gyula, Wright, Karen, Ward, Peter, Toth, Istvan   +3 more
openaire   +2 more sources

An Economical Synthesis of Lewis X, Sialyl Lewis X and Their α-Galactosyl Analogues

Journal of Carbohydrate Chemistry, 1997
Economical syntheses of the Lewis X trisaccharide 8 and sialyl Lewis X tetrasaccharide 18 epitopes and the syntheses of the α-galactosyl epimers 9 and 20 of these structures are described. Thioglycosides 2, 5, 11 and 15 were used as glycosyl donors to construct the desired compounds in a stepwise manner in dimethyl(methylthio)sulphonium triflate ...
Dekany, Gyula, Wright, Karen, Toth, Istvan   +2 more
openaire   +2 more sources