Results 41 to 50 of about 91,795 (159)

The Role of Signal Transducer and Activator of Transcription 3 (STAT3) in Tumor Immunity

Indonesian Biomedical Journal, 2012
BACKGROUND: Inflammation is a key component of the tumor microenvironment. Cancer-associated inflammation is marked by the presence of specific inflammatory cells and inflammatory mediators.
Oeij Anindita Adhika, M Nurhalim Shahib
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The signal transducer and activator of transcription factors lodge in immunopathogenesis of rheumatoid arthritis

Reumatismo, 2016
Rheumatoid arthritisis (RA) is a chronic autoimmune disorder that affects ~1-2% of the world’s population and damages synovial joints. RA is characterized by inflammation, autoantibody production, cartilage and bone destruction and synovial hyperplasia ...
F. Zare, M. Dehghan-Manshadi, A. Mirshafiey   +2 more
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TYK2 in Immune Responses and Treatment of Psoriasis

Journal of Inflammation Research, 2022
Lin Shang,* Jiali Cao,* Siqi Zhao, Jingya Zhang, Yanling He Department of Dermatology, Capital Medical University Affiliated Beijing Chaoyang Hospital, Beijing, People’s Republic of China*These authors contributed equally to this ...
Shang L, Cao J, Zhao S, Zhang J, He Y
doaj  

The effects of signal transducer and activator of transcription three mutations on human platelets

Platelets, 2018
Involvement of signal transducer and activator of transcription 3 (STAT3) in inflammation is well known. Recently, a role for STAT3 in platelet activation and platelet production has been suggested.
Floor E. Aleva, Frank L. van de Veerdonk, Yang Li, Rahajeng N. Tunjungputri, Sami Simons, Philip G. De Groot, Mihai M. Netea, Yvonne F. Heijdra, Quirijn de Mast, André J.A.M. van der Ven   +9 more
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STAT2 (Signal Transducer and Activator of Transcription 2) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2017
Review on STAT2, with data on DNA, on the protein encoded, and where the gene is implicated.
openaire   +2 more sources

The Suppression of Signal Transducer and Activator of Transcription-3 in A549 human Lung Carcinoma Cells Induced by Marine Sponge Callyspongia aerizusa

Journal of Experimental Pharmacology
Yuni Elsa Hadisaputri,1,* Annida Adha Nurhaniefah,1,* Mutakin Mutakin,2 Rini Hendriani,3 Andri Rezano,4 Iyan Sopyan,5 Yusnaini Yusnaini,6 Yonathan Asikin,7 Rizky Abdulah3 1Department of Pharmaceutical Biology, Faculty of Pharmacy, Universitas ...
Hadisaputri YE, Nurhaniefah AA, Mutakin M, Hendriani R, Rezano A, Sopyan I, Yusnaini Y, Asikin Y, Abdulah R   +8 more
doaj  

GdX inhibits the occurrence and progression of breast cancer by negatively modulating the activity of STAT3

Cancer Biology & Therapy
Aim To elucidate the biological functionality and regulatory mechanisms of GdX in breast cancer (BC).Methods The examination of GdX expression in human BC tissues and cell lines was conducted through immunohistochemical (IHC) and Western blot.
Zhilin Chen, Lu Xu, Shibin Lin, Hongjun Huang, Qing Long, Jiwei Liu   +5 more
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Knockdown of long non-coding RNA HOXD-AS1 inhibits gastric cancer cell growth via inactivating the JAK2/STAT3 pathway

Tumor Biology, 2017
Long non-coding RNA HOXD-AS1 (HOXD cluster antisense RNA 1) has been demonstrated to be closely associated with the progression of several tumors. However, the biological function of HOXD-AS1 and the underlying molecular mechanism in gastric cancer are ...
Li Zheng, Jiangtao Chen, Zhongyong Zhou, Zhikuan He   +3 more
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Anti-Inflammatory Effects of Cannabigerol In Vitro and In Vivo Are Mediated Through the JAK/STAT/NFκB Signaling Pathway

Cells
Cannabinoid compounds have potential as treatments for a variety of conditions, with cannabigerol (CBG) being known for its anti-inflammatory properties. In this study, we investigated the effects of CBG in a cellular model of 1-chloro-2,4-dinitrobenzene
Ga Hee Jeong, Ki Chan Kim, Ji Hyun Lee
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Stimulatory role of interleukin 10 in CD8 T cells through STATs in gastric cancer

Tumor Biology, 2017
CD8 + T cells are considered to be critical in tumor surveillance and elimination. Increased CD8 + T cell frequency and function is associated with better prognosis in cancer patients. Interleukin 10 is a cytokine with controversial roles in CD8 + T cell–
Jianjun Xi, Mingzheng Xu, Zongchang Song, Hongqiang Li, Shumin Xu, Chunmei Wang, Haihan Song, Jianwen Bai   +7 more
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