Results 51 to 60 of about 90,535 (152)
Nardilysin promotes hepatocellular carcinoma through activation of signal transducer and activator of transcription 3 [PDF]
Cancer Science, 2017 Nardilysin (NRDC) is a metalloendopeptidase of the M16 family. We previously showed that NRDC activates inflammatory cytokine signaling, including interleukin‐6‐signal transducer and activator of transcription 3 (STAT3) signaling. NRDC has been implicated in the promotion of breast, gastric and esophageal cancer, as well as the development of liver ...
Yosuke Kasai +15 more
openaire +2 more sources
Effect and Mechanism of Running on Mouse Emphysema Model Induced by Cigarette Extract
康复学报, 2022 ObjectiveTo observe the effect of running on mouse emphysema model induced by cigarette extract, and to explore its mechanism based on signal transducer and activator of transcription 3 (STAT3).MethodsA total of 40 male C57BL/6 mice were randomly divided
LI Yongrong +3 more
doaj
Signal transducer and activator of transcription 3 (STAT3) signaling in retinal pigment epithelium cells [PDF]
JAK-STAT, 2013 The retinal pigmented epithelium (RPE) is a monolayer of specialized epithelial cells located between the photoreceptors of the retina and the choroidal blood supply. The RPE is essential for maintaining retinal health and vision. Recent findings identified STAT3 as a newly recognized regulator of RPE survival, inflammatory response, visual cycle ...
Patel, Amit K +2 more
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Supplementary Figure 3 from Activated Signal Transducer and Activator of Transcription (STAT) 3
, 2023 Supplementary Figure 3 from Activated Signal Transducer and Activator of Transcription (STAT ...
Denise J. Montell +4 more
openaire +1 more source
Signal transducer and activator of transcription 3 (STAT3) [PDF]
Science-Business eXchange, 2014 +8 more sources
Signal Transducer and Activator of Transcription 3 in Liver Diseases: A Novel Therapeutic Target
International Journal of Biological Sciences, 2011 Signal transducer and activator of transcription 3 (STAT3) is a transcription factor that is activated by many cytokines and growth factors and plays a key role in cell survival, proliferation, and differentiation.
Hua Wang, Fouad Lafdil, Xiaoni Kong, Bin Gao
doaj
口腔疾病防治, 2020 Objective To elucidate the role of signal transducer and activator of transcription 3 on orthodontic tooth movement, aiming at providing evidence for improving orthodontic bone modeling and remodeling. Methods Orthodontic tooth movement (OTM) models were
ZHANG Cheng +6 more
doaj +1 more source
Role of Janus kinase 1 and signal transducer and activator of transcription 3 in vitiligo
Clinical, Cosmetic and Investigational Dermatology, 2019 Rehab M Samaka,1 Mohammed A Basha,2 Dina Menesy31Department of Pathology, Faculty of Medicine, Menoufia University, Shibīn al Kawm, Egypt; 2Department of Dermatology, Andrology and STDs, Faculty of Medicine, Menoufia University, Shibīn al Kawm, Egypt ...
Samaka RM, Basha MA, Menesy D
doaj
Tumor Biology, 2017 Long non-coding RNA HOXD-AS1 (HOXD cluster antisense RNA 1) has been demonstrated to be closely associated with the progression of several tumors. However, the biological function of HOXD-AS1 and the underlying molecular mechanism in gastric cancer are ...
Li Zheng +3 more
doaj +1 more source
Signal transducer and activator of transcription 3 regulation by novel binding partners
World Journal of Biological Chemistry, 2015 Signal transducers and activators of transcription (STATs) mediate essential signals for various biological processes, including immune responses, hematopoiesis, and neurogenesis. STAT3, for example, is involved in the pathogenesis of various human diseases, including cancers, autoimmune and inflammatory disorders. STAT3 activation is therefore tightly
Matsuda, Tadashi +6 more
openaire +3 more sources