Results 121 to 130 of about 1,569,209 (311)
Groups for TGF-β1 signaling pathway experiments. [PDF]
, 2014 Groups for TGF-β1 signaling pathway experiments.
Li Wen (169316) +8 more
core +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Signaling pathway map screened by Metadrug. [PDF]
, 2014 Signaling pathway map screened by Metadrug.
P. K. Murthy (191191) +7 more
core +1 more source
Magnolol alleviates inflammation and oxidative stress in COPD via MAPK and Nrf2 signaling pathways
Current Research in BiotechnologyChronic obstructive pulmonary disease (COPD) is a chronic and progressive lung disease which is closely related to inflammation and oxidative-stress. Magnolol (MAG) is a polyphenolic compound that possesses extensive pharmacological actions, including ...
Simei Liu +9 more
doaj +1 more source
Frontiers in Oncology, 2019 Background and Objective: Exosome component 5 (EXOSC5) is a novel cancer-related gene that is aberrantly expressed in various malignances. However, the molecular mechanism and biological role of EXOSC5 have not been explored in colorectal cancer (CRC ...
Hongda Pan +11 more
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Mechanistic Genes of the Calcium Signaling Pathway. [PDF]
, 2012 Mechanistic Genes of the Calcium Signaling Pathway.
Sangeeta Khare (141487) +11 more
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source