A Herpes Simplex Virus 2 (HSV-2) Glycoprotein D-expressing Nonreplicating Dominant-Negative HSV-2 Virus Vaccine Is Superior to a gD2 Subunit Vaccine against HSV-2 Genital Infection in Guinea Pigs [PDF]
We recently constructed a novel non-replicating dominant-negative HSV-2 recombinant viral vaccine (CJ2-gD2) capable of expressing various HSV-2 antigens that are dominant targets of HSV-2-specific CD8 T-cell response.
Balliet, John W.+4 more
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In vitro anti-herpeticactivityofanaqueousextractfromtheplant Phyllanthus orbicularis [PDF]
The Herpesviridae includes atleasteightviralspeciespathogenicforhumans,responsibleforawidevarietyof clinicalsymptoms.Thelackofaneffectivevaccineandthemoderatetohightoxicityoftheavailablesyntheticanti- herpescompoundsemphasisestheneedfornewinhibitors ...
Alvarez, Angel L.+5 more
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Complete genome sequence of cercopithecine herpesvirus 2 (SA8) and comparison with other simplexviruses [PDF]
We have obtained the complete sequence of the herpesvirus simian agent 8 (SA8; cercopithecine herpesvirus 2) a baboon simplexvirus closely related to the monkey B virus and herpes simplex virus types 1 and 2. The genome of SA8 is 150,715 bp long, with an
Peters, Geoffrey A.+2 more
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Een patient met opportunistische infecties als gevolg van het verworven immuundeficientie syndroom [PDF]
Contains fulltext : 4432.pdf (publisher's version ) (Open ...
Franken, C.+3 more
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Cryo-electron tomography of Kaposi\u27s sarcoma-associated herpesvirus capsids reveals dynamic scaffolding structures essential to capsid assembly and maturation. [PDF]
Kaposi\u27s sarcoma-associated herpesvirus (KSHV) is a recently discovered DNA tumor virus that belongs to the gamma-herpesvirus subfamily. Though numerous studies on KSHV and other herpesviruses, in general, have revealed much about their multilayered ...
Deng, Binbin+3 more
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Isolation and characterization of the herpes simplex virus 1 terminase complex [PDF]
During herpes simplex virus 1 (HSV-1) infection, empty procapsids are assembled and subsequently filled with the viral genome by means of a protein complex called the terminase, which is comprised of the HSV-1 UL15, UL28, and UL33 proteins.
Heming, Jason D+3 more
core +2 more sources
David gegen Goliath : wie Viren das Immunsystem überlisten [PDF]
Infektionen mit Herpesviren sind bereits seit der Antike bekannt. So beschrieb zum Beispiel schon Hippokrates in seinem »Corpus Hippocraticum« die sich auf der Haut ausbreitenden Herpes Simplex Läsionen und gab der Krankheit ihren bis heute gültigen ...
Schölz, Christian, Tampé, Robert
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Hemophagocytic syndrome caused by primary herpes simplex virus 1 infection: report of a first case [PDF]
Introduction: Hemophagocytic syndrome represents a severe hyperinflammatory condition by activated macrophages. Leading viral triggering agents are Epstein-Barr virus (EBV), cytomegalovirus (CMV), and adenovirus.
Bossart, W.+9 more
core
A red/far-red light-responsive bi-stable toggle switch to control gene expression in mammalian cells [PDF]
Growth and differentiation of multicellular systems is orchestrated by spatially restricted gene expression programs in specialized subpopulations. The targeted manipulation of such processes by synthetic tools with high-spatiotemporal resolution could ...
Busacker, Moritz+5 more
core +1 more source