An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Efficacy and safety of high-intensity focused ultrasound versus cryoablation for breast fibroadenomas: a systematic review and meta-analysis. [PDF]
Zhao Y, Sun J, Lin S.
europepmc +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Does a low-carbohydrate diet impede endurance sports performance? Yes. [PDF]
Burke LM, Noakes TD.
europepmc +1 more source
Impact of heated tobacco products on biomarkers of potential harm and adverse events: a systematic review and meta-analysis. [PDF]
Braznell S +3 more
europepmc +1 more source
Short-term coastal forest responses to a hurricane-scale freshwater and saltwater flooding experiment. [PDF]
Myers-Pigg AN +13 more
europepmc +1 more source
Joint modeling of longitudinal and time-to-event data for dynamic disease risk prediction using proteomics. [PDF]
Lindén M +4 more
europepmc +1 more source
Endovascular ablation of the right greater splanchnic nerve for the management of heart failure with preserved ejection fraction: a systematic review and meta-analysis. [PDF]
Manea H +11 more
europepmc +1 more source
Automated ROI detection allows rapid quantification of synaptic activity across tens of thousands of synapses in cell culture. [PDF]
Begley JC, Prüss H, Turko P, Dean C.
europepmc +1 more source

