Results 11 to 20 of about 352,666 (292)
The role of NLRP3 inflammasome in inflammation-related skeletal muscle atrophy
Frontiers in Immunology, 2022 Skeletal muscle atrophy is a common complication in survivors of sepsis, which affects the respiratory and motor functions of patients, thus severely impacting their quality of life and long-term survival.
Yukun Liu +6 more
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Skeletal muscle atrophy: From mechanisms to treatments.
Pharmacological Research, 2021 Skeletal muscle is a crucial tissue for movement, gestural assistance, metabolic homeostasis, and thermogenesis. It makes up approximately 40% of the total body weight and 50% of total protein. However, several pathological abnormalities (e.g., chronic diseases, cancer, long-term infection, aging) can induce an imbalance in skeletal muscle protein ...
Lin Yin +6 more
semanticscholar +3 more sources
Frontiers in Pharmacology, 2022 Skeletal muscle atrophy is a common and serious complication of chronic kidney disease (CKD). Oxidative stress and mitochondrial dysfunction are involved in the pathogenesis of muscle atrophy.
Qiang Li +9 more
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Mechanisms of skeletal muscle atrophy in type 2 diabetes mellitus [PDF]
Frontiers in PhysiologyIntroductionERS-induced apoptosis may play a pivotal role in diabetic skeletal muscle atrophy. However, the specific mechanisms by which ERS regulates skeletal muscle atrophy in diabetes remain unclear.
Jingyi Yang +4 more
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Resistance Exercise Counteracts Skeletal Muscle Atrophy in T2DM Mice by Upregulating FGF21 and Activating PI3K/Akt Pathway [PDF]
BiomoleculesDecreased skeletal muscle mass and function are a serious complication of long-term diabetes, often leading to numerous adverse outcomes. The primary pathological features of diabetic sarcopenia include muscle fiber atrophy and interstitial fibrosis ...
Xiaojie Ma +5 more
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Chronic systemic inflammation by peptidoglycan‐polysaccharide induces skeletal muscle atrophy in male and ovariectomized C57BL/6J mice [PDF]
Physiological ReportsChronic systemic inflammation (CSI) induces skeletal muscle atrophy. The severity of tissue damage caused by CSI varies according to sex. However, there are still many unknowns regarding the sex differences in skeletal muscle atrophy in patients with CSI.
Ryoga Kinoshita +7 more
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RETRACTED: Nestin Regulates Autophagy‐Dependent Ferroptosis Mediated Skeletal Muscle Atrophy by Ubiquitinating MAP 1LC3B [PDF]
Journal of Cachexia, Sarcopenia and MuscleBackground Programmed cell death plays a critical role in skeletal muscle atrophy. Ferroptosis, an iron‐dependent form of programmed cell death driven by lipid peroxidation, has been implicated in various diseases, but its role in skeletal muscle atrophy
Shunshun Han +8 more
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JCSM CommunicationsBackground Terpenoids have gained attention as therapeutic agents for skeletal muscle atrophy owing to their various physiological activities. In this study, we screened four terpenoids for their therapeutic potential against muscle atrophy in cultured ...
Yuki Enoki +4 more
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Role of Exercise in Skeletal Muscle Atrophy: A Mechanistic Investigation [PDF]
운동과학, 2020 PURPOSE Skeletal muscle atrophy induces overall health problems and many related diseases in older adults. In particular, sarcopenia is related to lowered quality of life, decreased physical activity, high levels of morbidity and mortality owing to ...
Dae Yun Seo +3 more
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The Functional Role of Long Non-Coding RNA in Myogenesis and Skeletal Muscle Atrophy
Cells, 2022 Skeletal muscle is a pivotal organ in humans that maintains locomotion and homeostasis. Muscle atrophy caused by sarcopenia and cachexia, which results in reduced muscle mass and impaired skeletal muscle function, is a serious health condition that ...
Keisuke Hitachi +2 more
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