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Astragaloside IV Alleviates Lupus Nephritis by Inhibiting Podocyte Ferroptosis via the PI3K/AKT/Nrf2 Pathway. [PDF]
Tang Z, Cheng L, Li M, Huang C.
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PRMT5 inhibition sensitizes B-cell lymphoma cells to ferroptosis. [PDF]
Liu Y +14 more
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Inflammatory CD4<sup>+</sup> T cells can waive NRF2-dependent SLC7A11-mediated cystine uptake by using ASCT1. [PDF]
Neullens CT +8 more
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BCAA catabolism mediates POU2AF1 propionylation to enhance T-ALL development. [PDF]
Dan S +13 more
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Ferroptosis and Neurodegenerative Diseases: Insights into the Regulatory Roles of SLC7A11
Cellular and Molecular Neurobiology, 2023Programed cell death plays a key role in promoting human development and maintaining homeostasis. Ferroptosis is a recently identified pattern of programmed cell death that is closely associated with the onset and progression of neurodegenerative diseases. Ferroptosis is mainly caused by the intracellular accumulation of iron-dependent lipid peroxides.
Chen Wang, Haihui Liu, Si Xu
exaly +3 more sources
Die Pharmazie, 2017
Antisense lncRNAs play a key role in the progression of multiple cancers. Thus, it is important to elucidate the function and mechanism of antisense lncRNAs, which may play a role in the treatment of epithelial ovarian cancer (EOC). In the current study, for the first time, we showed that the level of As-SLC7A11 was markedly reduced in EOC cancer ...
Jinjin Yuan, Jinjin Yuan +2 more
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Antisense lncRNAs play a key role in the progression of multiple cancers. Thus, it is important to elucidate the function and mechanism of antisense lncRNAs, which may play a role in the treatment of epithelial ovarian cancer (EOC). In the current study, for the first time, we showed that the level of As-SLC7A11 was markedly reduced in EOC cancer ...
Jinjin Yuan, Jinjin Yuan +2 more
openaire +2 more sources
SLC7A11/xCT Prevents Cardiac Hypertrophy by Inhibiting Ferroptosis
Cardiovascular Drugs and Therapy, 2021Systemic hypertension may induce adverse hypertrophy of the left cardiac ventricle. Pathological cardiac hypertrophy is a common cause of heart failure. We investigated the significance of ferroptosis repressor xCT in hypertrophic cardiomyopathy.xCT expression in angiotensin II (Ang II)-treated mouse hearts and rat cardiomyocytes was determined using ...
Xiyu, Zhang +11 more
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