Results 241 to 250 of about 23,034 (273)

A spinal USP7-Bach1 positive feedback loop drives NOX4-mediated ferroptosis in neuropathic pain. [PDF]

open access: yesRedox Biol
Jiao B   +7 more
europepmc   +1 more source

PDHA1-acetylation signaling suppresses cuproptosis to attenuate anti-androgen effect in prostate cancer. [PDF]

open access: yesCell Death Dis
Zhuang R   +12 more
europepmc   +1 more source

Slc7a11 Modulated by POU2F1 is Involved in Pigmentation in Rabbit [PDF]

open access: yesInternational Journal of Molecular Sciences, 2019
Abstract Solute carrier family 7 member 11 (Slc7a11) codes for a cystine/glutamate xCT transporter and can control production of pheomelanin pigment to change fur and skin colors of animals. Previous studies found that the skin expression levels of Slc7a11 varied significantly with the fur colors of the Rex Rabbit.
Bohao Zhao, Xinsheng Wu
exaly   +3 more sources

Kynurenine importation by SLC7A11 propagates anti-ferroptotic signaling

open access: yesMolecular Cell, 2022
IDO1 oxidizes tryptophan (TRP) to generate kynurenine (KYN), the substrate for 1-carbon and NAD metabolism, and is implicated in pro-cancer pathophysiology and infection biology. However, the mechanistic relationships between IDO1 in amino acid depletion versus product generation have remained a longstanding mystery.
Alessandra Fiore   +2 more
exaly   +4 more sources

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