Results 11 to 20 of about 348,107 (298)
Endogenous small interfering RNAs in animals [PDF]
Nature Reviews Molecular Cell Biology, 2008 Until recently, only nematodes among animals had a well-defined endogenous small interfering RNA (endo-siRNA) pathway. This has changed dramatically with the recent discovery of diverse intramolecular and intermolecular substrates that generate endo-siRNAs in Drosophila melanogaster and mice.
Katsutomo, Okamura, Eric C, Lai
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Frontiers in Bioinformatics, 2022 The enzyme Dicer is a component of many small RNA (sRNA) pathways involved in RNA processing for post-transcriptional regulation, anti-viral response and control of transposable elements.
Ben Murcott +5 more
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Small Interfering RNA- Modern Approach for Intervening Pathological Conditions
NUST Journal of Natural Sciences, 2021 RNA interference (RNAi) refers to the inhibition of gene expression by small double-stranded RNA molecules. This technology can prove to be a breakthrough biological discovery of the decade as it has the potential to revolutionize the field of ...
Shazia Choudhary +7 more
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Small interfering RNA inhibition of Andes virus replication. [PDF]
PLoS ONE, 2014 Andes virus (ANDV) is the most common causative agent of hantavirus pulmonary syndrome (HPS) in the Americas, and is the only hantavirus associated with human-to-human transmission. Case fatality rates of ANDV-induced HPS are approximately 40%. There are
Cheng-Feng Chiang +3 more
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Potential Application of Small Interfering RNA in Gastro-Intestinal Tumors
Pharmaceuticals, 2022 Despite the progress made in the diagnoses and therapy of gastrointestinal cancers, these diseases are still plagued by a high mortality. Thus, novel therapeutic approaches are urgently required.
Pasquale Losurdo +10 more
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A small interfering RNA (siRNA) database for SARS-CoV-2
Scientific Reports, 2021 Coronavirus disease 2019 (COVID-19) rapidly transformed into a global pandemic, for which a demand for developing antivirals capable of targeting the SARS-CoV-2 RNA genome and blocking the activity of its genes has emerged.
Inácio Gomes Medeiros +5 more
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Small interfering RNAs in tendon homeostasis
British Medical Bulletin, 2021 Abstract Background Tenogenesis and tendon homeostasis are guided by genes encoding for the structural molecules of tendon fibres. Small interfering RNAs (siRNAs), acting on gene regulation, can therefore participate in the process of tendon healing ...
Gargano, Giuseppe +3 more
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Small Interfering RNA in Colorectal Cancer Liver Metastasis Therapy
Technology in Cancer Research & Treatment, 2022 Colorectal cancer (CRC) is associated with numerous genetic disorders and cellular abnormalities, and liver metastasis is a common health concern in patients with CRC.
Junlin Xie MM, Shubin Wang MD
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Traffic into silence: endomembranes and post-transcriptional RNA silencing. [PDF]
, 2014 microRNAs (miRNAs) and small interfering RNAs (siRNAs) are small RNAs that repress gene expression at the post-transcriptional level in plants and animals. Small RNAs guide Argonaute-containing RNA-induced silencing complexes to target RNAs in a sequence-
Chen, Xuemei +2 more
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Recent studies on non-coding small RNAs in plants
浙江大学学报. 农业与生命科学版, 2014 There are many non-coding small RNAs in plants and animals, which regulate gene expression via direct cleavage of target mRNAs or via inhibition of translation at the post-transcriptional level.
Shen Enhui +3 more
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