Results 1 to 10 of about 1,407,145 (245)
Small RNA transcriptome analysis using parallel single-cell small RNA sequencing
Scientific Reports, 2023 miRNA and other forms of small RNAs are known to regulate many biological processes. Single-cell small RNA sequencing can be used to profile small RNAs of individual cells; however, limitations of efficiency and scale prevent its widespread application ...
Jia Li +4 more
doaj +3 more sources
BMC Biology, 2023 Background A fraction of all genomes is composed of transposable elements (TEs) whose mobility needs to be carefully controlled. In gonads, TE activity is repressed by PIWI-interacting RNAs (piRNAs), a class of small RNAs synthesized by heterochromatic ...
Amna Asif-Laidin +8 more
doaj +1 more source
Current Biology, 2007 PIWI-interacting RNAs (piRNAs), 24–30 nucleotide long RNAs found in the germ cells of animals, are unique among small silencing RNAs in that they require neither an RdRP nor Dicer for their production (Figure 1Figure 1C). Instead, they are thought to derive from single-stranded precursor RNAs tens or hundreds of thousands of nucleotides long.
Matranga, Christian, Zamore, Phillip D.
openaire +2 more sources
Nucleic Acids Research, 1996 The small RNA database is a compilation of all the small size RNA sequences available to date, including nuclear, nucleolar, cytoplasmic and mitochondrial small RNAs from eukaryotic organisms and small RNAs from prokaryotic cells as well as viruses. Currently, about 600 small RNA sequences are in our database.
J, Gu, Y, Chen, R, Reddy
openaire +6 more sources
Mechanistic insights into non-coding Y RNA processing
RNA Biology, 2022 Y RNAs (84–112 nt) are non-coding RNAs transcribed by RNA polymerase III and are characterized by a distinctive secondary structure. Human Y RNAs interact with the autoimmune proteins SSB and RO60 that together form a ribonucleoprotein (RNP) complex ...
Martina Billmeier +7 more
doaj +1 more source
Non-Coding RNA, 2020 vtRNA2-1 is a vault RNA initially classified as microRNA precursor hsa-mir-886 and recently proposed as “nc886”, a new type of non-coding RNA involved in cancer progression acting as an oncogene and tumor suppressor gene in different tissues.
Rafael Sebastián Fort +3 more
doaj +1 more source
Cold Spring Harbor Perspectives in Biology, 2013 In plants, RNA silencing is a fundamental regulator of gene expression, heterochromatin formation, suppression of transposable elements, and defense against viruses. The sequence specificity of these processes relies on small noncoding RNA (sRNA) molecules.
Dunoyer, P. +3 more
openaire +3 more sources
Early Drought-Responsive Genes Are Variable and Relevant to Drought Tolerance
G3: Genes, Genomes, Genetics, 2020 Drought stress is an important crop yield limiting factor worldwide. Plant physiological responses to drought stress are driven by changes in gene expression.
Cheng He +7 more
doaj +1 more source
sRNA23, a novel small RNA, regulates to the pathogenesis of Streptococcus suis serotype 2
Virulence, 2021 Streptococcus suis serotype 2 (S. suis 2) is an important ubiquitous zoonotic pathogen. To date, regulatory factors and their implication in S. suis pathogenesis are not fully understood.
Quanming Xu +7 more
doaj +1 more source
, 2010 The next generation sequencing technologies have made the exhaustive sequencing of all small RNA species within a small RNA library possible. Thus, comparative studies on the changes in small-RNA transcriptomes between two biological samples represent a powerful means of revealing the functions of small RNAs in physiological and pathological processes.
Seungil, Ro, Wei, Yan
openaire +2 more sources