Results 21 to 30 of about 1,407,145 (245)
Cells, 2020 The Dicer protein is one of the most important components of RNAi machinery because it regulates the production of small RNAs (sRNAs) in eukaryotes. Here, Dicer1-like gene (Pit-DCL1) and Dicer2-like gene (Pit-DCL2) RNAi transformants were generated via ...
Chunxiao Yin +4 more
doaj +1 more source
Journal of Cell Science, 2003 Small RNAs have burst on the scene as ubiquitous, versatile repressors of gene expression in plants, animals and many fungi. These tiny RNAs (∼21-26 nt), which induce silencing through homologous sequence interactions, come in many guises: short interfering (si) RNAs ([Elbashir et al., 2001][1]),
E Jean, Finnegan, Marjori A, Matzke
openaire +2 more sources
Extracting Small RNAs from Human Biological Fluids for Subsequent Next-Generation Sequencing
Креативная хирургия и онкология, 2019 A number of questions arise when choosing methods for experiments related to next-generation sequencing. On the one hand, while working with RNA extraction, added reagents and their residues can often inhibit sensitive chemicals with which the sequential
O. A. Beylerli +2 more
doaj +1 more source
Transfer RNA-derived small RNA: an emerging small non-coding RNA with key roles in cancer
Experimental Hematology & Oncology, 2022 Transfer RNAs (tRNAs) promote protein translation by binding to the corresponding amino acids and transporting them to the ribosome, which is essential in protein translation.
Xinliang Gu +5 more
doaj +1 more source
Small RNAs, Big Diseases [PDF]
International Journal of Molecular Sciences, 2020 The past two decades have seen extensive research done to pinpoint the role of microRNAs (miRNAs) that have led to discovering thousands of miRNAs in humans. It is not, therefore, surprising to see many of them implicated in a number of common as well as rare human diseases.
Iwona Rzeszutek, Aditi Singh
openaire +3 more sources
One Small RNA of Fusarium graminearum Targets and Silences CEBiP Gene in Common Wheat
Microorganisms, 2019 The pathogenic fungus Fusarium graminearum (F. graminearum), causing Fusarium head blight (FHB) or scab, is one of the most important cereal killers worldwide, exerting great economic and agronomic losses on global grain production.
Jiao Jian, Xu Liang
doaj +1 more source
Small RNA modifications: regulatory molecules and potential applications
Journal of Hematology & Oncology, 2023 Small RNAs (also referred to as small noncoding RNAs, sncRNA) are defined as polymeric ribonucleic acid molecules that are less than 200 nucleotides in length and serve a variety of essential functions within cells.
Qunli Xiong, Yaguang Zhang
doaj +1 more source
Bacterial Small RNA Regulators [PDF]
Critical Reviews in Biochemistry and Molecular Biology, 2005 Small regulatory RNAs can modify the activity of proteins and the stability and translation of mRNAs. They have now been found in a wide range of organisms, and can play previously unsuspected critical regulatory roles. The bacterial small RNAs include two major classes.
Nadim, Majdalani +2 more
openaire +2 more sources
BMC Genomics, 2020 Background The RNA interference (RNAi) pathway is a gene regulation mechanism that utilizes small RNA (sRNA) and Argonaute (Ago) proteins to silence target genes.
Hanbang Zhang +3 more
doaj +1 more source
Cell Reports, 2019 Summary: MicroRNA (miRNA) processing begins with Drosha cleavage, the fidelity of which is critical for downstream processing and mature miRNA target specificity.
Xavier Bofill-De Ros +11 more
doaj +1 more source