Results 31 to 40 of about 1,842 (145)
Frontiers in Endocrinology, 2022 Autosomal Dominant Polycystic Kidney Disease (ADPKD) is an inherited disorder characterized by the development of renal cysts, which frequently leads to renal failure.
Valentina Carotti +8 more
doaj +1 more source
Animals, 2023 Skin lesions are a frequent fact associated with intensive conditions affecting farmed fish. Knowing that the use of probiotics can improve fish skin health, SpPdp11 dietary administration has demonstrated beneficial effects for farmed fish, so its ...
Isabel M. Cerezo +7 more
doaj +1 more source
Regulation of skeletal mineralisation by PHOSPHO1 [PDF]
, 2017 PHOSPHO1 is a skeletal specific phosphatase whose activity towards the lipid metabolites, phosphocholine (PCho) and phosphoethanolamine (PEth), results in the generation of inorganic phosphate (Pi) within matrix vesicles (MV).
Houston, Dean Alexander
core +3 more sources
, 2022 Duchenne muscular dystrophy (DMD) is caused by loss-of-function mutations in the dystrophin gene on chromosome Xp21. Disruption of the dystrophin–glycoprotein complex (DGC) on the cell membrane causes cytosolic Ca2+ influx, resulting in protease ...
Takashi Okada +3 more
core +1 more source
Increased PHOSPHO1 and Alkaline Phosphatase expression during the anabolic bone response to intermittent parathyroid hormone delivery:Control of PHOSPHO1 and TNAP expression by iPTH [PDF]
, 2022 The administration of intermittent parathyroid hormone (iPTH) is anabolic to the skeleton. Recent studies with cultured osteoblasts have revealed that the expression of PHOSPHO1, a bone-specific phosphatase essential for the initiation of mineralisation,
Stephen, Louise A. +29 more
core +1 more source
Nasal Transcriptome and Epigenome Analysis Identifies the Pathogenic Features of Aspirin-Exacerbated Respiratory Disease [PDF]
, 2023 Dysregulation of the arachidonic acid metabolic pathway is the most widely known pathomechanism of aspirin-exacerbated respiratory disease (AERD). This study aimed to perform integrative analysis of transcriptomic and epigenomic profiling with network ...
Tae-Wook Kang +13 more
core +1 more source
Developmental Dynamics, EarlyView.Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini +2 more
wiley +1 more source
Frontiers in Endocrinology, 2023 IntroductionDue to a lack of spatial-temporal resolution at the single cell level, the etiologies of the bone dysfunction caused by diseases such as normal aging, osteoporosis, and the metabolic bone disease associated with chronic kidney disease (CKD ...
Rafiou Agoro +23 more
doaj +1 more source
Advanced Science, Volume 13, Issue 55, 5 October 2026.This study unravels that bone fracture accelerates diabetic wound healing by releasing exosomal microRNA (miR‐130b‐3p). To mimic this bone‐skin crosstalk, we engineered a self‐assembling agomir‐130b‐3p nanocomplex. Delivered via a photocrosslinkable hydrogel, this bio‐inspired therapy provides sustained localized agomir release.
Tao Shen +14 more
wiley +1 more source
Nucleic Acids as Emerging Regulators of Calcium Phosphate Biomineralization
The FASEB Journal, Volume 40, Issue 17, 15 September 2026.Calcium phosphate biomineralization has traditionally been considered a protein‐regulated process. This review highlights the emerging role of nucleic acids, which interact with mineral phases through adsorption, coprecipitation, and templating, thereby influencing crystal nucleation and growth.
Fanny Duhalde +2 more
wiley +1 more source