Results 21 to 30 of about 2,855 (178)
SND1 overexpression deregulates cholesterol homeostasis in hepatocellular carcinoma
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2016 SND1 is a multifunctional protein participating, among others, in gene transcription and mRNA metabolism. SND1 is overexpressed in cancer cells and promotes viability and tumourigenicity of hepatocellular carcinoma cells.
Rueda Estévez, Yuri +2 more
core +4 more sources
Molecular and cellular insights into the role of SND1 in lipid metabolism
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2020 Staphylococcal nuclease and Tudor domain containing 1 (SND1) is an evolutionarily conserved protein present in eukaryotic cells from protozoa to mammals.
Rueda Estévez, Yuri +6 more
core +4 more sources
Breast Cancer Research, 2023 Background SND1 participates in tumorigenesis, tumour invasion and metastasis in different cancers. Previous studies have shown that SND1 can promote the invasion and migration of breast cancer cells.
Huibian Zhang +3 more
doaj +2 more sources
The RNA‐binding protein Snd1/Tudor‐SN regulates hypoxia‐responsive gene expression [PDF]
FASEB BioAdvances, 2023 Snd1 is an evolutionarily conserved RNA‐binding protein implicated in several regulatory processes in gene expression including activation of transcription, mRNA splicing, and microRNA decay.
Juha Saarikettu +9 more
doaj +4 more sources
European Journal of Medical Research, 2023 Recently, evidence has suggested a regulatory role for SND1 in osteoarthritis progression. Interestingly, we found that SND1 protein expression was increased, mitochondria were shrunken and decreased in number, mitochondrial membrane potential was ...
Shufeng Lin +4 more
doaj +2 more sources
The multifaceted oncogene SND1 in cancer: focus on hepatocellular carcinoma
Hepatoma Research, 2018 Staphylococcal nuclease and tudor domain containing 1 (SND1) is a protein that regulates a complex array of functions. It controls gene expression through transcriptional activation, mRNA degradation, mRNA stabilization, ubiquitination and alternative ...
Mendoza, Rachel +3 more
core +4 more sources
The Tudor SND1 protein is an m6A RNA reader essential for replication of Kaposi’s sarcoma-associated herpesvirus [PDF]
eLife, 2019 N6-methyladenosine (m6A) is the most abundant internal RNA modification of cellular mRNAs. m6A is recognised by YTH domain-containing proteins, which selectively bind to m6A-decorated RNAs regulating their turnover and translation.
Belinda Baquero-Perez +5 more
doaj +2 more sources
Biomedicines, 2023 Long non-coding RNAs (lncRNAs), typically more than 200 nt long, cannot encode proteins, but can regulate gene expression. They play an indispensable role in the occurrence and progression of various cancers.
Xuke Qin +4 more
doaj +2 more sources
SND1-Targeted Gene Therapy for Hepatocellular Carcinoma [PDF]
, 2018 Staphylococcal nuclease and tudor-domain containing 1 (SND1) is an oncogene for a wide variety of cancers, including hepatocellular carcinoma (HCC). SND1 is a multifunctional protein regulating gene expression of proto-oncogenes and tumor suppressor ...
Mckiver, Bryan D
core +2 more sources
LncRNA Snhg3 aggravates hepatic steatosis via PPARγ signaling [PDF]
eLifeLncRNAs are involved in modulating the individual risk and the severity of progression in metabolic dysfunction-associated fatty liver disease (MASLD), but their precise roles remain largely unknown.
Xianghong Xie +22 more
doaj +2 more sources