Results 61 to 70 of about 778,801 (197)

Use of Solid Dispersion Systems in Pharmacy

open access: yesКонденсированные среды и межфазные границы, 2020
An overview of the use of solid dispersion systems in pharmacy is presented. The main techniques of obtaining solid dispersions were considered. The simplest one is the solvent removal technique: the medicinal drug and the carrier are dissolved in the ...
Sof ’ya Yu. Silaeva   +6 more
doaj   +1 more source

Preparation, characterization, and in vitro/vivo evaluation of polymer-assisting formulation of atorvastatin calcium based on solid dispersion technique

open access: yesAsian Journal of Pharmaceutical Sciences, 2018
Due to low solubility and bioavailability, atorvastatin calcium is confronted with challenge in conceiving appropriate formulation. Solid dispersion of atorvastatin calcium was prepared through the solvent evaporation method, with Poloxamer 188 as ...
Wenxiang Dong   +5 more
doaj   +1 more source

Discontinuous shear modulus determines the glass transition temperature

open access: yes, 2015
A solid - amorphous or crystalline - is defined by a finite shear modulus while a fluid lacks such. We thus experimentally investigate the elastic properties of a colloidal glass former near the glass transition: spectroscopy of vibrational excitations ...
Keim, Peter   +2 more
core   +2 more sources

Development of megestrol acetate solid dispersion nanoparticles for enhanced oral delivery by using a supercritical antisolvent process

open access: yesDrug Design, Development and Therapy, 2015
Eun-Sol Ha,1 Jeong-Soo Kim,2 In-hwan Baek,3 Jin-Wook Yoo,1 Yunjin Jung,1 Hyung Ryong Moon,1 Min-Soo Kim1 1College of Pharmacy, Pusan National University, 2Dong-A ST Co Ltd, Yongin, 3College of Pharmacy, Kyungsung University, Busan, South Korea Abstract:
Ha ES   +6 more
doaj  

Pharmaceutical Dispersion Techniques for Dissolution and Bioavailability Enhancement of Poorly Water-Soluble Drugs

open access: yesPharmaceutics, 2018
Over the past decades, a large number of drugs as well as drug candidates with poor dissolution characteristics have been witnessed, which invokes great interest in enabling formulation of these active ingredients.
Xingwang Zhang   +3 more
doaj   +1 more source

A solid dispersion based on milk-micelle as a drug-carrier for the enhancement of the aqueous solubility of ritonavir [PDF]

open access: yes, 2015
The goal of present investigation was to evaluate the feasibility of formulating a solid-dispersion using milk-micelles as drug-carriers, to enhance the aqueous solubility of ...
Bernardez, M.   +5 more
core   +1 more source

Selection of Solubility Enhancement Technologies for S-892216, a Novel COVID-19 Drug Candidate

open access: yesPharmaceutics
Background/Objectives: S-892216 is a poorly water-soluble drug developed as a novel oral treatment for COVID-19, although its oral absorption is low. For Phase 1 (Ph1) studies and commercial use, both oral solution and solid dispersion technologies are ...
Ryo Ohashi   +7 more
doaj   +1 more source

Advantages of using YBCO-Nanowire-YBCO heterostructures in the search for Majorana Fermions

open access: yes, 2012
We propose an alternative platform to observe Majorana bound states in solid state systems. High critical temperature cuprate superconductors can induce superconductivity, by proximity effect, in quasi one dimensional nanowires with strong spin orbit ...
Lucignano, P.   +3 more
core   +1 more source

The Effect of Relative Sediment Volume on Sheet Properties of Coated Paper [PDF]

open access: yes, 1967
The degree of dispersion of pigment has been claimed to be an important variable in the determination of sheet properties such as smoothness and gloss. The degree of dispersion of a pigment can be related to relative sediment volume (RSV) by comparison ...
Chalfin, James A.
core   +1 more source

In Situ Absorption in Rat Intestinal Tract of Solid Dispersion of Annonaceous Acetogenins

open access: yesGastroenterology Research and Practice, 2012
Isolated from Annona squamosa L, Annonaceous acetogenins (ACGs) exhibit a broad range of biological properties yet absorbed badly due to the low solubility.
Yun-Jie Dang   +4 more
doaj   +1 more source

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