Results 61 to 70 of about 780,981 (298)
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Российский паразитологический журналThe purpose of the research is to study the anthelmintic efficacy of complex solid dispersion of fenbendazole and niclozamide against dictyocaulosis and trichuriosis of sheep.Materials and methods.
A. I. Varlamova +5 more
doaj +1 more source
Molecules, 2015 The present study aimed to investigate the effect of Eudragit® E/HCl (E-SD) on the degradation of sirolimus in simulated gastric fluid (pH 1.2) and to develop a new oral formulation of sirolimus using E-SD solid dispersions to enhance oral ...
Youngseok Cho +5 more
doaj +1 more source
Disolusi Asam Mefenamat Dalam Sistem Dispersi Padat Dengan Peg 4000 [PDF]
, 2014 Mefenamic acid is an analgetic that insoluble in water and classified into class II in theBiopharmaceutic Classification System (BCS), therefore the dissolution become the rate limitingstep of absorption process and bioavailability.
Sugiyono, S. (Sugiyono) +2 more
core
The phonon dispersion of graphite revisited [PDF]
, 2004 We review calculations and measurements of the phonon-dispersion relation of graphite. First-principles calculations using density-functional theory are generally in good agreement with the experimental data since the long-range character of the ...
Rubio, Angel, Wirtz, Ludger
core +3 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Influence of dispersion aluminum powder on the burning rate of mixed solid fuel
MATEC Web of Conferences, 2018 In work results of experimental study of influence dispersion of metal powder on burning rate in mixed solid fuel are provided. As metal fuel used additive of aluminum of different type depending on dispersion of powder.
Zolotorev Nikolay +2 more
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
EFEK ULCEROGENIC DISPERSI PADAT IBUPROFEN-POLIVINILPIROLIDON (PVP) PADA TIKUS PUTIH JANTAN
Pharmaciana, 2013 Ibuprofen is an anti inflammatory, analgesic, and antipyretic agent. It has low solubility and bioavailability. The administration of ibuprofen in a long time and high dose can increased of side effect at gastrointestinal (peptic ulcer). This study was
Ririt Vita Febrianti , Iis Wahyuningsih
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source