Peptide-directed crystal growth modification in the formation of ZnO [PDF]
, 2015 Biomolecule-mediated synthesis is fascinating in terms of the level of control and the intricate hierarchical structures of the materials that can be produced.
Liang, M-K +3 more
core +1 more source
Synthesis and cellular penetration properties of new phosphonium based cationic amphiphilic peptides [PDF]
, 2018 A new category of phosphonium based cationic amphiphilic peptides has been developed and evaluated as potential antimicrobial peptides and cell penetrating peptides.
Gannon, Susan +7 more
core +1 more source
Solid Phase versus Solution Phase Synthesis of Heterocyclic Macrocycles
Molecules, 2013 Comparing a solution phase route to a solid phase route in the synthesis of the cytotoxic natural product urukthapelstatin A (Ustat A) confirmed that a solid phase method is superior.
Shelli R. McAlpine, Seong Jong Kim
doaj +1 more source
Epimerisation in Peptide Synthesis
Molecules, 2023 Epimerisation is basically a chemical conversion that includes the transformation of an epimer into another epimer or its chiral partner. Epimerisation of amino acid is a side reaction that sometimes happens during peptide synthesis.
Suleman Duengo +4 more
doaj +1 more source
Synthesis of cyclotetrapeptide analogues of c-PLAI and evaluation of their antimicrobial properties [PDF]
Royal Society Open Science, 2021 Antimicrobial peptides (AMPs) are interesting compounds owing to their ability to kill several pathogens. In order to identify new AMPs, c-PLAI analogues were synthesized and evaluated together with their linear precursors for their antimicrobial ...
Rani Maharani +8 more
doaj +1 more source
HOBt·DCHA-Mediated Synthesis of Sterically Hindered Peptides employing Fmoc-Amino Acid Chlorides in Both Solution-Phase and Solid Phase Methods [PDF]
, 2008 The synthesis of peptides employing Fmoc-amino acid chlorides in presence of HOBt·DCHA salt in solution as well as by the solid-phase methods is described. The coupling was found to be complete in 30 min and free from racemization.
Krishna, G.C. +2 more
core +1 more source
ChemSusChem, 2020 Solid-phase peptide synthesis (SPPS) is the method of choice for the preparation of peptides in both, laboratory scale and large production. Although the methodology has been improved during the last decades allowing the achievement of long peptides and ...
Ashish Kumar +4 more
semanticscholar +1 more source
Nucleic Acid Carriers Based on Precise Polymer Conjugates [PDF]
, 2011 Polymer polydispersity, random conjugation of functional groups, and poorly understood structure–activity relationships have constantly hampered progress in the development of nucleic acid carriers.
Troiber, Christina, Wagner, Ernst
core +1 more source
Exploration of the one-bead one-compound methodology for the design of prolyl oligopeptidase substrates. [PDF]
PLoS ONE, 2009 Here we describe the design, synthesis and evaluation of the first solid-phase substrates for prolyl oligopeptidase (POP), a cytosolic serine peptidase associated with schizophrenia, bipolar affective disorder and related neuropsychiatric disorders. This
Gemma Comellas +4 more
doaj +1 more source
The Synthesis of cis- and trans-Fused Bicyclic Sugar Amino Acids [PDF]
, 2006 Four isomeric bicyclic sugar amino acids (SAAs) were prepared from an α-acetylenic-C-glucoside by employing a Petasis olefination and a ring-closing metathesis (RCM) as key steps.
Anelli +37 more
core +2 more sources