Synthesis, screening, and sequencing of cysteine-rich one-bead one-compound peptide libraries. [PDF]
Cysteine-rich peptides are valued as tags for biarsenical fluorophores and as environmentally important reagents for binding toxic heavy metals. Due to the inherent difficulties created by cysteine, the power of one-bead one-compound (OBOC) libraries has
Greaves, John +3 more
core +2 more sources
Deprotection Reagents in Fmoc Solid Phase Peptide Synthesis: Moving Away from Piperidine? [PDF]
Luna OF +5 more
europepmc +3 more sources
On the selection and design of proteins and peptide derivatives for the production of photoluminescent, red-emitting gold quantum clusters [PDF]
Novel pathways of the synthesis of photoluminescent gold quantum clusters (AuQCs) using biomolecules as reactants provide biocompatible products for biological imaging techniques.
A Baksi +48 more
core +2 more sources
Solid Phase Formylation of N-Terminus Peptides
Formylation of amino groups is a critical reaction involved in several biological processes including post-translational modification of histones. The addition of a formyl group (CHO) to the N-terminal end of a peptide chain generates biologically active
Anna Lucia Tornesello +2 more
doaj +1 more source
Synthesis of a Cyclooctapeptide, Cyclopurpuracin, and Evaluation of Its Antimicrobial Activity
Cyclopurpuracin is a cyclooctapeptide isolated from the methanol extract of Annona purpurea seeds with a sequence of cyclo-Gly-Phe-Ile-Gly-Ser-Pro-Val-Pro.
Rani Maharani +9 more
doaj +1 more source
Conformational photoswitching of a synthetic peptide foldamer bound within a phospholipid bilayer [PDF]
The dynamic properties of foldamers, synthetic molecules that mimic folded biomolecules, have mainly been explored in free solution.We report on the design, synthesis, and conformational behavior of photoresponsive foldamers bound in a phospholipid ...
Clayden, Jonathan +5 more
core +2 more sources
Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang +6 more
wiley +1 more source
Cyclo19,31[D-Cys19]-uPA19-31 is a potent competitive antagonist of the interaction of urokinase-type plasminogen activator with its receptor (CD87) [PDF]
Urokinase-type plasminogen activator (uPA) represents a central molecule in pericellular proteolysis and is implicated in a variety of physiological and pathophysiological processes such as tissue remodelling, wound healing, tumor invasion, and ...
Arroyo de Prada, Nuria +10 more
core +1 more source
Structural and functional characterization of chitinase from carnivorous plant Drosera adelae
A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda +7 more
wiley +1 more source
A tetrapeptide, an analog of trypsin-modulating oostatic factor (TMOF), has been synthesised by using a method of solid-phase peptide synthesis on 2-chlorotrityl chloride resin. Fmoc strategy was applied on the synthesis.
Rani Maharani, Eka Fitri Yanti
doaj +1 more source

