Results 51 to 60 of about 5,620 (124)
Pro‐Inflammatory c‐Met+ CD4 T Cells in Multiple Sclerosis
Annals of Neurology, Volume 99, Issue 1, Page 261-273, January 2026.Objective Hepatocyte growth factor (HGF) binds exclusively the c‐Met surface receptor, and the HGF/c‐Met axis regulates T cell function in autoimmune diseases. We analyzed c‐Met expression on human CD4 T cells in the blood and cerebrospinal fluid (CSF) from patients with multiple sclerosis (MS) versus non‐inflammatory neurological disease (NIND), to ...
Gautier Breville +6 more
wiley +1 more source
Immunological Reviews, Volume 337, Issue 1, January 2026.ABSTRACT The intestinal immune system is constantly challenged to distinguish between innocuous dietary antigens, commensal microbiota and intestinal self‐antigens (self‐Ags) versus harmful pathogens and malignant cells. It resides in the intestinal wall itself, Peyer's patches (PPs) and the draining lymph nodes (LNs).
Yixuan D. Zhou +2 more
wiley +1 more source
PLoS ONE, 2014 BackgroundMesenchymal stem cells have prominent immune modulatory properties, which may have clinical applications; however their major source, bone marrow, is of limited availability.
Fernando de Sá Silva +11 more
doaj +1 more source
Advanced Science, Volume 12, Issue 48, December 29, 2025.Polysaccharides modulate immune responses by engaging pattern recognition receptors (PRRs) to induce T‐cell activation. In vaccine design, their particle size critically influences lymph node targeting and activation mechanisms. By engineering structural complexity and multivalent PRR engagement, polysaccharides enable precise modulation of immune ...
Jeong Hyun Moon +8 more
wiley +1 more source
PLoS ONE, 2013 Common variable immunodeficiency (CVID) is characterized by defective B cell function, impaired antibody production, and increased susceptibility to bacterial infections.
Dominic Paquin-Proulx +9 more
doaj +1 more source
Soluble CD14 and CD83 from Human Neonatal Antigen-Presenting Cells Are Inducible by Commensal Bacteria and Suppress Allergen-Induced Human Neonatal Th2 Differentiation [PDF]
Infection and Immunity, 2007 ABSTRACTCD14 is expressed on the cell surface of various antigen-presenting cells, and CD83 is a maturation marker for dendritic cells (DC). CD14 and CD83 are also present as soluble proteins, and both have immunoregulatory functions. We examined whether neonatal cord blood monocytes or DC released soluble CD14 (sCD14) or sCD83 when exposed to the ...
Anna-Carin, Lundell +4 more
openaire +2 more sources
European Journal of Immunology, Volume 55, Issue 12, December 2025.We optimised a protocol for mHA‐specific Treg (mTreg) selection in an HLA‐matched context while defining its phenotype, transcriptional state and function. mTreg were highly activated and exerted specific, HLA class II‐, contact‐dependent suppression. This protocol can be explored as a highly personalised antigen‐specific Treg‐based therapy in future ...
Carolina Paulino Pacini +5 more
wiley +1 more source
Immunobiology, 2006 A soluble form of CD83 ("sCD83") has been shown to block DC-mediated T cell stimulation in vitro and an immunosuppressive role has also been shown in vivo using an experimental-autoimmune-encephalomyelits (EAE) model. Using recombinant mutational analyses, recently, we could show that sCD83 forms a homo-dimer, whereby four cysteines are involved in the
Elisabeth, Zinser +4 more
openaire +2 more sources
Curcumin's Therapeutic Potential in Ovarian Cancer: Current Insights and Future Perspectives
Food Science &Nutrition, Volume 13, Issue 12, December 2025.This review provides an overview of ovarian cancer, examines curcumin's emerging role in its treatment, identifies existing research gaps, and outlines a roadmap for future studies aimed at fully exploring curcumin's therapeutic potential in the management of ovarian cancer.
Smirnova Elena +7 more
wiley +1 more source
Cell Transplantation, 2014 Cells derived from the placenta have become the focus of extensive research concerning their ability to be used for regenerative medicine or cellular therapies.
Richard Banas M.S. +3 more
doaj +1 more source