Results 31 to 40 of about 136,487 (285)
Human Pancreas GH-Releasing Factor Analog Restores High-Amplitude GH Pulses in CNS Lesion-Induced GH Deficiency [PDF]
, 1983 Lesions of the ventromedial-arcuate (VMH-ARC) region of the hypothalamus result in impaired growth accompanied by a marked suppression in spontaneous GH secretory bursts. We studied the effects of an analog of the recently characterized human pancreas GH-
Eikelboom, Rudy +2 more
core +2 more sources
Intranasal Insulin Mitigates Memory Impairment and Neuroinflammation in a Mouse Model of Hippocampal Aging. [PDF]
Pharmacol Res PerspectABSTRACT Aging is a complex process that frequently includes cognitive decline with memory loss. In the hippocampus, the number of somatostatin‐positive (Sst+) GABAergic interneurons in the hilar region of the dentate gyrus decreases with age. We previously showed that selective ablation of Sst+ dentate hilar interneurons is sufficient to induce ...
Nagarajan R +5 more
europepmc +2 more sources
Targeted radiotherapy of neuroblastoma: future directions [PDF]
, 2017 No abstract ...
Gaze, Mark N. +4 more
core +2 more sources
Treatment options for PNET liver metastases. a systematic review [PDF]
, 2018 Pancreatic neuroendocrine tumors (PNETs) are rare pancreatic neoplasms. About 40-80% of patients with PNET are metastatic at presentation, usually involving the liver (40-93%). Liver metastasis represents the most significant prognostic factor.
Aurello, Paolo +8 more
core +1 more source
Angewandte Chemie, EarlyView.A one‐step multi‐component synthetic approach is reported to construct α‐aryl‐substituted DOTAs, which required tedious multi‐step synthesis in all previous works. The synthesized α‐aryl‐substituted DOTAs showed improved performance for developing multifunctional theranostics and represent a universal platform for bioconjugation. Abstract α‐Substituted
Pak‐Lun Lam +8 more
wiley +2 more sources
An expression signature of the angiogenic response in gastrointestinal neuroendocrine tumours: correlation with tumour phenotype and survival outcomes. [PDF]
, 2013 BACKGROUND: Gastroenteropancreatic neuroendocrine tumours (GEP-NETs) are heterogeneous with respect to biological behaviour and prognosis. As angiogenesis is a renowned pathogenic hallmark as well as a therapeutic target, we aimed to investigate the ...
A Couvelard +47 more
core +2 more sources
Frontiers in Molecular Neuroscience, 2020 Oxytocin, acting through the oxytocin receptor (Oxtr) in the periphery, is best known for its roles in regulating parturition and lactation. However, it is also now known to possess a number of important social functions within the central nervous system,
W. Scott Young, June Song
doaj +1 more source
Successful postoperative pancreatic fistula treatment with the use of somatostatin infusion after duodenal gastrointestinal stromal tumor resection [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2019 Introduction. According to the International Study Group on Pancreatic Fistula, a postoperative pancreatic fistula is defined as every case of fluid leak on the third (or later) postoperative day, in which the level of amylase in the collected fluid is ...
Chabowski Mariusz +6 more
doaj +1 more source
Poultry Science, 2021 : Melatonin (MEL) plays an important role in regulating growth and development of organisms and the cellular metabolism. This study was conducted to explore the role of MEL in mediating monochromatic light-induced secretion of somatostatin (SST) in the ...
Xiaojing Qin +7 more
doaj +1 more source
Duodenal carcinoid tumour – a case report [PDF]
, 2020 Duodenal carcinoids are rare tumours of the small intestine with heterogenous clinical and pathological characteristics. The long-term prognosis is very good if discovered in the early stages.
Alexescu, Teodora Gabriela +7 more
core +2 more sources