Results 81 to 90 of about 675,123 (288)

Peptide receptor radionuclide therapy using radiolabeled somatostatin analogs: focus on future developments

Clinical and translational imaging, 2014
Peptide receptor radionuclide therapy (PRRT) has been shown to be an effective treatment for neuroendocrine tumors (NETs) if curative surgery is not an option. A majority of NETs abundantly express somatostatin receptors.
Sander M. Bison, M. Konijnenberg, M. Melis, S. Pool, M. Bernsen, Jaap J M Teunissen, D. Kwekkeboom, M. de Jong   +7 more
semanticscholar   +1 more source

GLP‐1 agonists and the gut microbiome: A bidirectional relationship

British Journal of Clinical Pharmacology, EarlyView.
Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists have transformed the management of type 2 diabetes mellitus (T2DM) and obesity, yet their interactions with the gut microbiome remain an emerging frontier in pharmacological and metabolic research.
Srinivas Kamath, Nicole S. L. Chan, Paul Joyce   +2 more
wiley   +1 more source

Risk factors and management of pasireotide-associated hyperglycemia in acromegaly

Endocrine Connections, 2020
Pasireotide, a multireceptor-targeted somatostatin analog with highest affinity for somatostatin receptor subtype (SST) 5, has demonstrated superio r efficacy over the SST2-preferential somatostatin analogs octreotide and lanreotide.
Mônica R Gadelha, Feng Gu, Marcello D Bronstein, Thierry C Brue, Maria Fleseriu, Ilan Shimon, Aart J van der Lely, Shoba Ravichandran, Albert Kandra, Alberto M Pedroncelli, Annamaria A L Colao   +10 more
doaj   +1 more source

Advances in Parahydrogen‐Induced Polarization for Nuclear Magnetic Resonance of Peptides, Proteins, and Biopolymers

ChemistryEurope, EarlyView.
Hyperpolarization by parahydrogen‐induced polarization enhances the sensitivity of nuclear magnetic resonance spectroscopy of amino acids, peptides, mini‐proteins, and biopolymers using nonnatural amino acids with unsaturated side chains up to three orders of magnitude.
Gerd Buntkowsky
wiley   +1 more source

Molecular Characterization of Growth Hormone-producing Tumors in the GC Rat Model of Acromegaly [PDF]

, 2015
D.A.C. was supported by the Nicolás Monardes program of the Andalusian Ministry of Health (C-0015-2014) and by a grant from the Andalusian Ministry of Science and Innovation (CTS-7478).
Balcerzyk, M, Cano, DA, Castano, JP, Fernandez-Maza, L, Ibanez-Costa, A, Leal-Campanario, R, Leal-Cerro, A, Luque, RM, Martin-Rodriguez, JF, Munoz-Bravo, JL, Soto-Moreno, A, Venegas-Moreno, E   +11 more
core   +3 more sources

Carbon Dots for Cancer Theranostics: Synthesis Strategies, Luminescence Properties, and Advances in Bioimaging‐Guided Diagnosis and Therapy

Chemistry – A European Journal, EarlyView.
Lighting up the path to precision oncology: This review comprehensively summarizes the rational design of carbon dots (CDs), elucidating how core size, surface chemistry, and heteroatom doping dictate their luminescence mechanisms. Special emphasis is placed on engineering NIR‐II emissive CDs for deep‐tissue imaging.
Zekun Yan, Yupeng Liu, Jinyun Tan, Songnan Qu   +3 more
wiley   +1 more source

Somatostatin and opioid receptors do not regulate proliferation or apoptosis of the human multiple myeloma U266 cells [PDF]

, 2009
International ...
Céline Kerros, Thibault Cavey, Brigitte Sola, Philippe Jauzac, Stéphane Allouche   +4 more
core   +1 more source

Continuous outcome estimation in N‐of‐1 trials for accelerated decision‐making

Epilepsia, EarlyView.
Abstract Objective N‐of‐1 trials aim to determine the therapeutic effect for a single individual. This individualized approach necessitates collecting multiple data points over time through repeated alternating periods of active treatment and a comparator or control condition.
Victoria Defelippe, František Bartoš, Eric‐Jan Wagenmakers, Kees P. J. Braun, Floor E. Jansen, Willem M. Otte   +5 more
wiley   +1 more source

Advances in the treatment of gastroenteropancreatic neuroendocrine tumors

Clinical and Experimental Gastroenterology, 2010
Pamela L Kunz, George A FisherStanford University Medical Center, CA, USAAbstract: Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are a rare and heterogeneous class of neoplasms.
Pamela L Kunz, George A Fisher
doaj  

A review of the use of somatostatin analogs in oncology

OncoTargets and Therapy, 2013
Somatostatin is a neuropeptide produced by paracrine cells that are located throughout the gastrointestinal tract, lung, and pancreas, and is also found in various locations of the nervous system.
O. Keskin, Ş. Yalçın
semanticscholar   +1 more source