Results 121 to 130 of about 26,431 (247)
HDL nanoparticles targeting sonic hedgehog subtype medulloblastoma
, 2018 Medulloblastoma is the most common paediatric malignant brain cancer and there is a need for new targeted therapeutic approaches to more effectively treat these malignant tumours, which can be divided into four molecular subtypes.
Jonathan B. Bell +6 more
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Aggregate, Volume 7, Issue 6, June 2026.This review surveys eukaryotic cilia as putative quantum‐enabled sensory and regulatory centers. It highlights their multifaceted roles in the cell, focuses on the nontrivial roles of quantum mechanics in their membrane and cytoskeletal proteins, and introduces the essential building blocks enabling quantum properties to survive in the warm, wet, and ...
Daniel L. Bilezikian +5 more
wiley +1 more source
The role of primary cilia and sonic hedgehog signalling in adrenal development function.
, 2012 PhDPrimary cilia are sensory organelles found on most vertebrate cells during interphase. They play key roles in development, cell signalling and cancer, and are involved in signal transduction pathways such as Hh and Wnt signalling.
Cogger, Kathryn
core
Sonic Hedgehog signaling in the mammalian brain.
, 2010 International audienceThe discovery of a Sonic Hedgehog (Shh) signaling pathway in the mature vertebrate CNS has paved the way to the characterization of the functional roles of Shh signals in normal and diseased brain.
Ruat, Martial +2 more
core +1 more source
, 2010 Efecto mitógeno de Sonic hedgehog (Shh) sobre precursores de oligodendrocitos y su uso en enfermedades desmielinizantes. La presente invención se refiere al efecto mitogénico de la proteína Sonic hedgehog (Shh) sobre células precursoras de ...
Bribián Arruego, Ana +4 more
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Sonic hedgehog Is Required Early in Pancreatic Islet Development
, 2002 Pancreatic organogenesis relies on a complex interplay of cell-autonomous and extracellular signals. We demonstrate that the morphogen sonic hedgehog (Shh) is required for pancreatic development in zebrafish.
Moss, Jennifer B. +9 more
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American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1179-1191, June 2026.ABSTRACT The ciliopathies are a group of genetic disorders caused by defective function of either the primary cilia (a large number) or the motile cilia (a much smaller number). These have been defined as diseases with mutations in genes encoding individual ciliary or cilia‐associated proteins.
Robert P. Erickson +1 more
wiley +1 more source
, 2006 Efecto mitógeno de Sonic hedgehog (Shh) sobre precursores de oligodendrocitos y su uso en enfermedades desmielinizantes. La presente invención se refiere al efecto mitogénico de la proteína Sonic hedgehog (Shh) sobre células precursoras de ...
Bribián Arruego, Ana +4 more
core
Annals of Neurology, Volume 99, Issue 6, Page 1571-1588, June 2026.Objective Cerebral ischemic stroke causes neuronal oxygen/energy deprivation, disrupting mitochondrial function including reduced membrane potential and bioenergetics, exacerbating neuronal injury. Mitochondrial defects are, therefore, a central neuropathological node and potential therapeutic target.
Ning Bian +9 more
wiley +1 more source
Hipospadias genetiğinde SHH (Sonic hedgehog) yolağının araştırılması
, 2020 ABSTRACTINVESTIGATION OF SHH (SONIC HEDGEHOG) PATH IN HYPOSPADIAS GENETICSHypospadias is one of the most common congenital anomalies of the genital system. Hypospadias has been shown to be associated with potentially impaired gene expressions, but the cause remains largely unknown.
openaire +1 more source