Results 21 to 30 of about 29,104 (247)

The SOS response regulates adaptive mutation [PDF]

Proceedings of the National Academy of Sciences, 2000
Upon starvation some Escherichia coli cells undergo a transient, genome-wide hypermutation (called adaptive mutation) that is recombination-dependent and appears to be a response to a stressful environment. Adaptive mutation may reflect an inducible mechanism that generates genetic variability in times of stress ...
G J, McKenzie, R S, Harris, P L, Lee, S M, Rosenberg   +3 more
openaire   +2 more sources

Growth‐dependent heterogeneity in the DNA damage response in Escherichia coli

Molecular Systems Biology, 2022
In natural environments, bacteria are frequently exposed to sub‐lethal levels of DNA damage, which leads to the induction of a stress response (the SOS response in Escherichia coli).
Sebastián Jaramillo‐Riveri, James Broughton, Alexander McVey, Teuta Pilizota, Matthew Scott, Meriem El Karoui   +5 more
doaj   +1 more source

The SOS response is permitted in Escherichia coli strains deficient in the expression of the mazEF pathway. [PDF]

PLoS ONE, 2014
The Escherichia coli (E. coli) SOS response is the largest, most complex, and best characterized bacterial network induced by DNA damage. It is controlled by a complex network involving the RecA and LexA proteins.
Ziva Kalderon, Sathish Kumar, Hanna Engelberg-Kulka   +2 more
doaj   +1 more source

A Decrease in the Daily Maximum Temperature during Global Warming Hiatus Causes a Delay in Spring Phenology in the China–DPRK–Russia Cross-Border Area

Remote Sensing, 2022
Spring phenology is the most sensitive indicator of climate change and exploring its response to climate change has important implications for ecosystem processes in the study area.
Minshu Su, Xiao Huang, Zhen Xu, Weihong Zhu, Zhehao Lin   +4 more
doaj   +1 more source

Spring Phenological Sensitivity to Climate Change in the Northern Hemisphere: Comprehensive Evaluation and Driving Force Analysis

Remote Sensing, 2021
Plant phenology depends largely on temperature, but temperature alone cannot explain the Northern Hemisphere shifts in the start of the growing season (SOS).
Kaiwei Li, Chunyi Wang, Qing Sun, Guangzhi Rong, Zhijun Tong, Xingpeng Liu, Jiquan Zhang   +6 more
doaj   +1 more source

The SOS Response Controls Integron Recombination

Science, 2009
Bacteria can mobilize antibiotic resistance under stressful conditions.
Guérin, Emilie, Cambray, Guillaume, Sanchez-Alberola, Neus, Campoy, Susana, Erill, Ivan, da Re, Sandra, Gonzalez-Zorn, Bruno, Barbé, Jordi, Ploy, Marie-Cécile, Mazel, Didier   +9 more
openaire   +5 more sources

Lipocalin‐2 activates hepatic stellate cells and promotes nonalcoholic steatohepatitis in high‐fat diet–fed Ob/Ob mice

Hepatology, EarlyView., 2022
Graphical summary of obesity‐induced NASH progression by LCN2 targeted to HSC activation. Abstract Background and Aims In obesity and type 2 diabetes mellitus, leptin promotes insulin resistance and contributes to the progression of NASH via activation of hepatic stellate cells (HSCs).
Kyung Eun Kim, Jaewoong Lee, Hyun Joo Shin, Eun Ae Jeong, Hye Min Jang, Yu Jeong Ahn, Hyeong Seok An, Jong Youl Lee, Meong Cheol Shin, Soo Kyoung Kim, Won Gi Yoo, Won Ho Kim, Gu Seob Roh   +12 more
wiley   +1 more source

Quinolone Antibiotics: Resistance and Therapy

Infection and Drug Resistance, 2023
Kai Tang, Heng Zhao Fujian Provincial Key Laboratory of Innate Immune Biology, Fujian Normal University, Fujian, People’s Republic of ChinaCorrespondence: Heng Zhao, Fujian Provincial Key Laboratory of Innate Immune Biology, Fujian Normal University ...
Tang K, Zhao H
doaj  

Analysis of the SOS response of Vibrio and other bacteria with multiple chromosomes

BMC Genomics, 2012
Background The SOS response is a well-known regulatory network present in most bacteria and aimed at addressing DNA damage. It has also been linked extensively to stress-induced mutagenesis, virulence and the emergence and dissemination of antibiotic ...
Sanchez-Alberola Neus, Campoy Susana, Barbé Jordi, Erill Ivan   +3 more
doaj   +1 more source

Systematically Altering Bacterial SOS Activity under Stress Reveals Therapeutic Strategies for Potentiating Antibiotics

mSphere, 2016
The bacterial SOS response is a DNA damage repair network that is strongly implicated in both survival and acquired drug resistance under antimicrobial stress.
Charlie Y. Mo, Sara A. Manning, Manuela Roggiani, Matthew J. Culyba, Amanda N. Samuels, Paul D. Sniegowski, Mark Goulian, Rahul M. Kohli   +7 more
doaj   +1 more source