Results 61 to 70 of about 86,024 (165)

SUMOylation impairs the protein-protein interaction between Oct4 and Sox2.

, 2012
NIH3T3 cells were cotransfected with various combinations of Oct4/Oct4 K118R, Sox2/Sox2 K247R, HA-Sumo1 and HA-Ubc9 expression plasmids as indicated.
Lixia Yang (156282), Wenzhong Li (156311), Bo Tang (23472), Yong Zhang (5893), Zekun Guo (156269), Haibo Wu (156272), Juan Du (118107), Xiaohai Wang (156274), Liping Yang (156318), Yongyan Wu (156264), Xiaoyan Shi (156294)   +10 more
core   +1 more source

Ovarian-dedifferentiated endometrioid adenocarcinoma: A rare case report

Indian Journal of Pathology and Microbiology
We reported a case of dedifferentiated ovarian carcinoma in a 51-year-old woman. The microscopic tumor consisted of well-differentiated endometrioid carcinoma and undifferentiated carcinoma.
Cao Beibei, Zhen Junhai, Ru Guoqing, Peng Fang   +3 more
doaj   +1 more source

Transcripts regulated by SOX2.

, 2016
(A) Schematic representation of the research design employed to uncover the SOX2 transcriptome in GSC11 cells. (B) qRT-PCR and western blot confirmation of SOX2 inhibition in GSC11 cells after 72h of si-SOX2 or si-Scramble (si-Scrbl) transfection.
Elizabeth Guruceaga (46989), Naiara Martínez-Vélez (848143), Candelaria Gomez-Manzano (198862), Arlet M. Acanda de la Rocha (718229), Enric Xipell (848144), Marisol González-Huarriz (3138378), Marta M. Alonso (198833), Hernando López-Bertoni (3138375), Juan Fueyo (198861)   +8 more
core   +1 more source

Immunohistochemical (IHC) staining of SOX2 in CRC tissues.

, 2012
(A–D) IHC images of SOX2-positve colorectal cancer tissues. Arrows indicate patches of strong SOX2 staining could indicate active tumor invasion fronts of the tumor capsules. (E–F) IHC images of SOX2-negative colorectal cancer tissues.
Xu Han (141301), Biaoyang Lin (7188), Xiaoyan Lou (112950), Xuefeng Fang (141303), Wenchao Ding (141305), Ying Yuan (133529), Dasong Hua (112951), Gregory Foltz (141307), Leroy Hood (4322)   +8 more
core   +1 more source

METTL3 blocked the progression of diabetic retinopathy through m6A-modified SOX2

Open Medicine
We aimed to explore the regulatory effects of methyltransferase-like 3 (METTL3) on diabetic retinopathy (DR) by regulating the m6A modification of SOX2 mRNA and elucidating the underlying molecular mechanism.
Chen Xiujuan, Ling Qipeng, Xu Jie, Ye Yunyao, Dong Lili   +4 more
doaj   +1 more source

Expression of the stem cell markers NANOG and SOX2 in the cervical squamous carcinogenesis

Radiology and Oncology
The aim of the present study was to assess a diagnostic potential of stem cell markers NANOG and SOX2 for classifying cervical squamous intraepithelial lesions (SILs)/cervical intraepithelial neoplasia (CIN).
Koren Miha, Zlajpah Margareta, Poljak Mario, Komlos Kristina Fujs, Flezar Margareta Strojan   +4 more
doaj   +1 more source

Sox2-overexpressing neural stem cells alleviate ventricular enlargement and neurological dysfunction in posthemorrhagic hydrocephalus

Neural Regeneration Research
Neural stem cells (NSCs) have the potential for self-renewal and multidirectional differentiation, and their transplantation has achieved good efficacy in a variety of diseases.
Baocheng Gao, Haoxiang Wang, Shuang Hu, Kunhong Zhong, Xiaoyin Liu, Ziang Deng, Yuanyou Li, Aiping Tong, Liangxue Zhou   +8 more
doaj   +1 more source

Glioma SOX2 expression decreased after adjuvant therapy

BMC Cancer, 2019
Background SOX2 is regarded as an important marker in stem cell. The change of SOX2 expression after adjuvant therapy in high grade glioma (HGG) remains unknown so far.
Wei Yu, Xiaoqiu Ren, Chunxiu Hu, Yinuo Tan, Yongjie Shui, Zexin Chen, Lili Zhang, Jiaping Peng, Qichun Wei   +8 more
doaj   +1 more source

Principal modes of motion for the Oct4 and Sox2 proteins.

, 2016
(A) Dominant motions of Oct4 and Sox2 in the Oct4/Sox20bp complex. (B) Dominant motions of Oct4 and Sox2 in the Oct4/Sox23bp complex. The magnitudes and directions of motion of the residues are indicated by red arrows in the ribbon structure.
Masaud Shah (390960), Muhammad Ayaz Anwar (780436), Dhanusha Yesudhas (847724), Sangdun Choi (122038), Suresh Panneerselvam (5666563), Prasannavenkatesh Durai (122034)   +5 more
core   +1 more source

Activin and Hepatocyte Growth Factor Promotes Colorectal Cancer Stemness and Metastasis through FOXM1/SOX2/CXCR4 Signaling

Gut and Liver
Background/Aims: Cancer stem cells (CSCs) are believed to drive tumor development and metastasis. Activin and hepatocyte growth factor (HGF) are important cytokines with the ability to induce cancer stemness.
Hong Peng, Ting Ye, Lei Deng, Xiaofang Yang, Qingling Li, Jin Tong, Jinjun Guo   +6 more
doaj   +1 more source