Results 71 to 80 of about 86,024 (165)

TP63 and SOX2 staining in cervical biopsies.

, 2014
Immunohistochemical staining of cervical biopsies. Bars  =  50µm.(A) normal cervix no primary control; (B) normal cervix stained with anti-SOX2; (C) Squamous cell cervical carcinoma no primary control; (D) representative TP63, and (E) representative SOX2,
Kate Cuschieri (677763), Sharon Moncur (677754), Heather Cubie (677758), Alistair Williams (677760), Victoria McLoughlin (677761), Chara Charsou (677752), Laura Hoodless (677755), Duanduan Cong (677757), Camille Busby-Earle (677759), June Stewart (677753), John D. M. Campbell (677762), Sarah Howie (677764), Ramya Bhatia (677756), Maurice Canham (677751)   +13 more
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CARM1 mediates modulation of Sox2. [PDF]

, 2011
Sox2 is a key component of the transcription factor network that maintains the pluripotent state of embryonic stem cells (ESCs). Sox2 is regulated by multiple post-translational modifications, including ubiquitination, sumoylation, acetylation and ...
Shen Yu-fei, Zhang Ye, Hui Dai, Ye Zhang, Hai-yong Zhao, Zhao Hai-yong, Yu-fei Shen, Zhang Yan-jun, Dai Hui, Yan-jun Zhang   +9 more
core   +1 more source

Assessment of SOX2 performance as a marker for circulating cancer stem-like cells (CCSCs) identification in advanced breast cancer patients using CytoTrack system

Open Medicine
Recent studies have highlighted that one of the main drivers for metastatic formation and resistance to the therapy are circulating tumor cells (CTCs) and cancer stem-like cells (CSCs).
Szostakowska-Rodzoś Małgorzata, Fabisiewicz Anna, Myśliwy Izabella, Jagiełło-Gruszfeld Agnieszka, Konieczna Aleksandra, Grzybowska Ewa A.   +5 more
doaj   +1 more source

Effect of Sox2 Oct-3/4 and Sox11 overexpression on Sox2 promoter activity

, 2011
Copyright information:Taken from "Elevating the levels of Sox2 in embryonal carcinoma cells and embryonic stem cells inhibits the expression of Sox2:Oct-3/4 target genes"Nucleic Acids Research 2007;35(6):1773-1786.Published online 25 Feb 2007PMCID ...
Michelle Desler (29778), Angie Rizzino (29782), Janel Kopp (29776), Sunil Mallanna (29777), Brian Boer (29775), Phillip J. Wilder (29780), Cory Bernadt (29781), Harini Chakravarthy (29779)   +7 more
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SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells

eLife, 2016
The transcription factor SOX2 is central in establishing and maintaining pluripotency. The processes that modulate SOX2 activity to promote pluripotency are not well understood. Here, we show SOX2 is O-GlcNAc modified in its transactivation domain during
Samuel A Myers, Sailaja Peddada, Nilanjana Chatterjee, Tara Friedrich, Kiichrio Tomoda, Gregor Krings, Sean Thomas, Jason Maynard, Michael Broeker, Matthew Thomson, Katherine Pollard, Shinya Yamanaka, Alma L Burlingame, Barbara Panning   +13 more
doaj   +1 more source

Immunohistochemical profiling and neuroepithelial heterogeneity in immature ovarian teratomas: a retrospective digital pathology-based study

Open Medicine
Immature ovarian teratomas are rare malignant germ cell tumours with variable neuroepithelial differentiation and limited prognostic markers. Their grading is subjective and challenging, with heterogeneous clinical behaviour and limited therapeutic ...
Tavdgiridze Nino, Svanadze Tamar, Tevdorashvili George, Kepuladze Shota, Burkadze George   +4 more
doaj   +1 more source

Genetic and epigenetic modifications of Sox2 contribute to the invasive phenotype of malignant gliomas.

PLoS ONE, 2011
We undertook this study to understand how the transcription factor Sox2 contributes to the malignant phenotype of glioblastoma multiforme (GBM), the most aggressive primary brain tumor.
Marta M Alonso, Ricardo Diez-Valle, Lorea Manterola, Angel Rubio, Dan Liu, Nahir Cortes-Santiago, Leire Urquiza, Patricia Jauregi, Adolfo Lopez de Munain, Nicolás Sampron, Ander Aramburu, Sonia Tejada-Solís, Carmen Vicente, María D Odero, Eva Bandrés, Jesús García-Foncillas, Miguel A Idoate, Frederick F Lang, Juan Fueyo, Candelaria Gomez-Manzano   +19 more
doaj   +1 more source

SOX2 expression in different ovarian tumor cell lines.

, 2014
Semi-quantitative RT-PCR analysis of SOX2 in six ovarian tumor cell lines. (B) Western blot analysis of the SOX2 protein expression in corresponding cell lines. GAPDH was used for normalization.
Youji Feng (579192), Zhenbo Zhang (579190), Xiaojie Wang (166442), Qifeng Wang (123379), Xiaoning Ji (579188), Jiazhou Chen (579189), Xiaowei Xi (579191), Dong Yan (356556)   +7 more
core   +1 more source

NF-YA transcriptionally activates the expression of SOX2 in cervical cancer stem cells.

PLoS ONE, 2019
Roles for SOX2 have been extensively studied in several types of cancer, including colorectal cancer, glioblastoma and breast cancer, with particular emphasis placed on the roles of SOX2 in cancer stem cell. Our previous study identified SOX2 as a marker
Wen-Ting Yang, Zong-Xia Zhao, Bin Li, Peng-Sheng Zheng   +3 more
doaj   +1 more source

Получение и анализ поликлональных антител к рекомбинантному транскрипционному фактору SOX2 [PDF]

, 2013
Транскрипционный фактор Sox2, который экспрессируется в эмбриональных стволовых клетках, играет важную роль в самообновлении и поддержании плюрипотентности эмбриональных и индуцированных плюрипотентных стволовых клеток.
Хасенов, Б.Б., Балтабекова, М.Ж., Секенова, А.Е., Огай, В.Б.   +3 more
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