Results 41 to 50 of about 86,024 (165)
Sox2 modulation increases naïve pluripotency plasticity. [PDF]
, 2021 Induced pluripotency provides a tool to explore mechanisms underlying establishment, maintenance, and differentiation of naive pluripotent stem cells (nPSCs). Here, we report that self-renewal of nPSCs requires minimal Sox2 expression (Sox2-low).
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Analysis of the Oct4 and Sox2 expression in Oct4/Sox2-ATMSCs.
, 2015 (A) RT-PCR analysis revealed that the mRNA expression of Oct4 and Sox2 in Oct4/Sox2-ATMSCs were significantly higher than that in RFP-ATMSCs at 24 h post-transfection.
Hwa-Young Youn (713961) +7 more
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Cervical cancer cells with positive Sox2 expression exhibit the properties of cancer stem cells. [PDF]
PLoS ONE, 2014 BACKGROUND: Although Sox2 expression has been found in several types of cancer, it has not yet been used to identify or isolate CSCs in somatic carcinoma.
Xiao-Fang Liu +4 more
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Maintenance of Sox2 expression in neuroepithelial cells.
, 2013 Immunofluorescence staining of six week old Sox2Δ/Δ mice demonstrated Sox2-positive ciliated and Clara cells in control mice (A,C), the extensive deletion of Sox2, and the presence of rare ciliated and Clara cells lacking Sox2 in Sox2Δ/Δ mice (B,D ...
Valérie Besnard (140741) +7 more
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Specificity and application of SOX2 antibody
Poultry Science, 2020 Sox2 is known to play an important role in maintaining the totipotency and self-renewal of embryonic stem cells. The purpose of this study was to prepare an anti-chicken Sox2 polyclonal antibody using prokaryotic expression techniques, to evaluate its ...
Longqin Wei +11 more
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Biology of regeneration in earthworms: mechanisms, factors and molecular insights. A review
Romanian Journal of Ecology & Environmental ChemistryEarthworms are ecosystem engineers that play a vital role in soil structure, nutrient cycling, and ecological balance. Beyond their ecological importance, they exhibit remarkable regenerative potential, making them valuable models for studying cellular ...
AMAR KUMAR +7 more
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Zhongliu Fangzhi Yanjiu, 2018 Objective To investigate the role of High-mobility group box-1 (HMGB1) protein in regulating the expression of cancer stem cell markers Nanog, OCT4 and Sox2.
WANG Hua +4 more
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Sox2COIN is a functional conditional allele.
, 2013 (A) Efficient removal of the neo cassette by Flpe recombinase to generate a Sox2COIN/+ allele. Sox2+/+ (lane 1), Sox2COIN/+ (lane 2), Sox2COIN/COIN (lane 3), Sox2INV/+ (lane 4), Sox2βgeo2/+ (lane 5) E14.5 mice. PCR genotyping of (1) Sox2+/+, (2) Sox2COIN/
Anastasia Kotsoni (305456) +6 more
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Cellular Reprogramming Employing Recombinant Sox2 Protein [PDF]
, 2012 Induced pluripotent stem (iPS) cells represent an attractive option for the derivation of patient-specific pluripotent cells for cell replacement therapies as well as disease modeling. To become clinically meaningful, safe iPS cells need to be generated
Frank Edenhofer +3 more
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Mapping domains necessary for Sox2 to mediate its self-association.
, 2013 (A) 293T cells were transiently transfected with expression constructs for GFP-Sox2 and the Flag-Sox2 constructs indicated. Nuclear extracts (input lanes) used for co-immunoprecipitation of Flag-Sox2 constructs and associated proteins are presented as ...
Sunil K. Mallanna (173368) +3 more
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