Results 21 to 30 of about 86,024 (165)

Construction of recombinant sox2-encoding plasmids that regulate pluripotency of breast cancer stem cells from indonesian patient [PDF]

Pharmaciana, 2019
A therapy development with recombinant protein is a new and potential innovation to destroy cancer stem cells (CSCs). Various ways of killing CSCs include the provision of polyvalent anti-protein antibodies that code pluripotency.
Hanifah Rahmi, Tiodinar Theresia, Amarila Malik, Septelia Inawati Wanandi   +3 more
doaj   +1 more source

Correlation of CD133 and SOX2 Expression with Regional Lymph Nodes Metastatic Status in Invasive Breast Carcinoma of No Special Type

Indonesian Journal of Cancer, 2021
Background: CD133 overexpression can increase cell proliferation, migration, and epithelialmesenchymal transition that promotes metastasis. CD133 expression is induced by hypoxiainduced factor (HIF) which requires SOX2 binding in the promoter region ...
Sutrisno, Dyah Fauziah, Gondo Mastutik
doaj   +1 more source

SOX2-OE promotes HCMV gene transcription.

, 2023
SOX2 overexpressing (SOX2-OE) and control (Ctl) cells were generated from U251, U87, LN229, T98G, A172 and CCF cells by lentivirus transduction. The cells were infected with HCMV Towne strain at an MOI of 5 and collected at the indicated times for viral ...
Fei Hu (191861), Simon Rayner (117650), Yong Qiu (83780), Fang-Cheng Li (3384743), Shuang Cheng (610515), Han Cheng (475615), Le Wen (14587872), Xian-Zhang Wang (11680805), Jin-Yan Sun (11930542), Jian Chen (15340), William J. Britt (15295121), Yue-Peng Zhou (5337254), Qing-Yang Zhang (1401712), Xing-Jun Jiang (15295118), Min-Hua Luo (522503)   +14 more
core   +1 more source

SOX2 Represses Hepatitis B Virus Replication by Binding to the Viral EnhII/Cp and Inhibiting the Promoter Activation

Viruses, 2020
Hepatitis B virus (HBV) replication is controlled by four promoters (preS1, preS2, Cp, and Xp) and two enhancers (EnhI and EnhII). EnhII stimulates Cp activity to regulate the transcriptions of precore, core, polymerase, and pregenomic RNAs, and ...
Hua Yang, Jiayin Mo, Qi Xiang, Peiyi Zhao, Yunting Song, Ge Yang, Kailang Wu, Yingle Liu, Weiyong Liu, Jianguo Wu   +9 more
doaj   +1 more source

FOS Rescues Neuronal Differentiation of Sox2-Deleted Neural Stem Cells by Genome-Wide Regulation of Common SOX2 and AP1(FOS-JUN) Target Genes [PDF]

, 2021
The transcription factor SOX2 is important for brain development and for neural stem cells (NSC) maintenance. Sox2-deleted (Sox2-del) NSC from neonatal mouse brain are lost after few passages in culture.
Pagin, Miriam, Pavesi, Giulio,, Nicolis, Silvia K., Pitasi, Mattia,, Pavesi, Giulio, Miriam Pagin, Ngan, Chew-Yee,, Giulio Pavesi, Malighetti, Federica,, Chew-Yee Ngan, Pernebrink, Mattias,, Claudio Cantù, Pernebrink, Mattias, Silvia K. Nicolis, Ottolenghi, Sergio,, Cantù, Claudio,, Nicolis, Silvia K.,, Ngan, Chew-Yee, Sergio Ottolenghi, Mattias Pernebrink, Federica Malighetti, Pagin, Miriam,, Ottolenghi, Sergio, Pitasi, Mattia, Malighetti, Federica, Ngan, Chew Yee, Nicolis, Silvia K, Mattia Pitasi, Cantù, Claudio, Pitasi M., Malighetti F., Cantu C., Pavesi G., Pernebrink M., Nicolis S. K., Pagin M., Ngan C. -Y., Ottolenghi S.   +37 more
core   +1 more source

Decreased Sox2 messenger RNA expression in basal cell carcinoma

Indian Journal of Dermatology, 2020
Background: Sox2, zeb1, and p21 have been implicated in aggressive behavior of squamous cell carcinoma (SCC) and melanoma. However, their expression level in basal cell carcinoma (BCC) has not been elucidated.
Reza Ahmadi-Beni, Fatemeh Vand-Rajabpour, Mohamadreza Ahmadifard, Maryam Daneshpazhooh, Pedram Noormohammadpour, Javad Rahmati, Kambiz Kamyab Hesari, Mehdi Yaseri, Mina Tabrizi   +8 more
doaj   +1 more source

SOX2 FISH and SOX2 IHC.

, 2013
Above: representative FISH images of sinonasal squamous cell carcinoma samples without SOX2 amplification (A), SOX2 low level amplification (B) and SOX2 high level amplification (C).
Sebastian Huss (214135), Robert Kirsten (395014), Martin Braun (395010), Alina Franzen (395009), Maike Bode (395008), Friederike Göke (395006), Ropika Menon (395013), Stephan Ihrler (395012), Friedrich Bootz (395015), Andreas Schröck (395005), Patrick Wagner (395007), Abbas Agaimy (395011), Glen Kristiansen (76479), Claudia Lengerke (395016), Sven Perner (395017)   +14 more
core   +1 more source

Transcription factor Six2 induces a stem cell‐like phenotype in renal cell carcinoma cells

FEBS Open Bio, 2019
Renal cell carcinoma (RCC) accounts for 2–3% of adult malignant tumors, and the incidence of RCC worldwide has increased by about 2% over the past two decades.
Na Cheng, Hongjuan Li, Yan Han, Shuzhen Sun   +3 more
doaj   +1 more source

Human PPIN topological properties of 1TF (OCT4 or SOX2 or NANOG), 2TF (OCT4-SOX2 or OCT4-NANOG or SOX2-NANOG) and 3TF (OCT4-SOX2-NANOG) targets.

, 2014
Human PPIN topological properties of 1TF (OCT4 or SOX2 or NANOG), 2TF (OCT4-SOX2 or OCT4-NANOG or SOX2-NANOG) and 3TF (OCT4-SOX2-NANOG) targets.
Liangcai Zhang (156659), Jinlian Hua (182220), Shihua Zhang (21549), Guiyou Liu (224712), Lei Yang (102719), Yongshuai Jiang (194259), Rennan Feng (186785), Mingzhi Liao (473967), Leijie Li (623371)   +8 more
core   +1 more source

Sox2 expression in the spiral ganglion of Sox2-EGFP mice during cochlear development.

, 2017
A: A coronal cross section through the otic vesicle (OV) from E10.5 Sox2-EGFP mouse immunostained against Sox2 (red) and TuJ1 (white). Arrowheads indicate delaminating neuroblasts.
Teppei Noda (848954), Koji Nishimura (2077804), Alain Dabdoub (848958)   +2 more
core   +1 more source