Results 101 to 110 of about 33,731 (224)

SOX30 Governs Synaptonemal Complex Assembly and Homologous Recombination in Male Meiosis

Cell Proliferation, EarlyView.
The transcription factor SOX30 directly binds promoter regions of SYCE1 and SYCE2 to mediate their transcriptional activation, thereby enabling proper assembly of central elements within the synaptonemal complex. Structural destabilisation of the synaptonemal complex in Sox30 KK spermatocytes triggers synaptic discontinuity, impairs homologous ...
Kangle Liu, Wenfeng Zhang, Xiao Jiang, Jianping Chen, Lei Zhu, Zhonghao Zhang, Jing Gu, Lulu Guo, Lin Ao, Qing Chen, Lei Sun, Yuhan Hu, Xin Wang, Yaxin Liu, Jia Cao, Fei Han, Jinyi Liu   +16 more
wiley   +1 more source

Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche. [PDF]

, 2017
A major challenge in stem cell differentiation is the availability of bioassays to prove cell types generated in vitro are equivalent to cells in vivo. In the mouse, differentiation of primordial germ cell-like cells (PGCLCs) from pluripotent cells was ...
Chen, Di, Clark, Amander T, Hennebold, Jon D, Lam, Truong N, Meistrich, Marvin L, Mitchell, Jennifer M, Orwig, Kyle E, Peters, Karen A, Rojas, Ernesto J, Shetty, Gunapala, Sosa, Enrique, Sukhwani, Meena, Tailor, Ramesh C, Wu, Zhuang   +13 more
core   +2 more sources

Proteomic analysis of the zone of degeneration at the mitosis–meiosis transition stage in wild‐caught male catshark (Scyliorhinus canicula), correlated with an unusually high‐water temperature in the English Channel

Journal of Fish Biology, EarlyView.
Abstract In the context of current global change, variations in water temperature are one of the environmental conditions with serious consequences for marine life, including reproductive processes. In the small spotted catshark Scyliorhinus canicula, spermatogenesis occurs in spermatocysts composed of synchronously developing germ cells associated ...
Fabian Jeanne, Stanislas Pilet, Sean Heighton, Benoît Bernay, Pascal Sourdaine   +4 more
wiley   +1 more source

Simple Classification of Male Mouse Germ Cells using Hoechst 33258 Staining

Journal of Animal Reproduction and Biotechnology, 2015
In the study for a differentiation and development of spermatogonial cells, the researchers should commonly require a simple, fast and reasonable method that could evaluate the developmental stage of male germ cells without any damage and also ...
Kyoung Guk Kim, Young Sik Park
doaj   +1 more source

The Transition from Stem Cell to Progenitor Spermatogonia and Male Fertility Requires the SHP2 Protein Tyrosine Phosphatase [PDF]

, 2014
SHP2 is a widely expressed protein tyrosine phosphatase required for signal transduction from multiple cell surface receptors. Gain and loss of function SHP2 mutations in humans are known to cause Noonan and LEOPARD syndromes, respectively, that are ...
Feng, Gen‐sheng, King, Philip D., Lapinski, Philip E., Orwig, Kyle E., Phillips, Bart T., Puri, Pawan, Rajkovic, Aleksandar, Suzuki, Hitomi, Walker, William H.   +8 more
core   +1 more source

Plasticity in the reproductive biology of Yellowstone cutthroat trout Oncorhynchus virginalis bouvieri in Yellowstone Lake following lake trout Salvelinus namaycush invasion

Journal of Fish Biology, EarlyView.
Abstract Yellowstone cutthroat trout Oncorhynchus virginalis bouvieri in Yellowstone Lake are the focus of intensive conservation efforts due to the threat of predation by invasive lake trout Salvelinus namaycush. Suppression gillnetting has reduced the abundance of predatory lake trout, and the Yellowstone cutthroat trout population is recovering ...
Michelle A. Briggs, Molly A. H. Webb, Christopher S. Guy, Todd M. Koel   +3 more
wiley   +1 more source

Germ cell quantification in human fetal and prepubertal testis tissues: a comparison of current methodologies

Reproduction and Fertility
Methods to quantify germ cell number in human immature testicular tissues are essential to evaluate the impact of chemotherapy exposures and to optimise cryopreservation protocols used in fertility preservation for prepubertal boys.
Emma Kearney, David Greenald, Gabriele Matilionyte, Sheila Lane, Melissa D Tharmalingam, Jill Davies, Jan-Bernd Stukenborg, Grace Forsyth, Rod T Mitchell   +8 more
doaj   +1 more source

Women in space: A review of known physiological adaptations and health perspectives

Experimental Physiology, EarlyView.
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford, Danielle J. Carroll, Heather C. M. Allaway, Bonnie J. Dunbar, Aenor J. Sawyer   +4 more
wiley   +1 more source

THE EFFECT OF CHRONIC EXPOSURE OF NICOTINE INHALATION TO THE COUNT OF SPERMATOGONIA, SERTOLI CELLS AND LEYDIG CELLS OF YOUNG WHITE RAT WISTAR STRAIN

Jurnal Urologi Indonesia, 2019
Objective: To analyze the difference in the number of spermatogonia, leydig cells and sertoli cells in young age of  white mice Wistar strain after inhalation of chronic nicotine exposure.
Aril Rizaldi, Doddy M Soebadi, Soetojo Soetojo   +2 more
doaj   +1 more source

Analysis of the gene expression profile of mouse male meiotic germ cells [PDF]

, 2004
Wide genome analysis of difference in gene expression between spermatogonial populations from 7-day-old mice and pachytene spermatocytes from 18-day-old mice was performed using Affymetrix gene chips representing approximately 12,500 mouse known genes or
Capolunghi, F, Di Agostino, S, Dolci, S, Geremia, R, Grimaldi, P, Loiarro, M, Martegani, E, Merico, D, Paronetto, M, Pellegrini, M, Rossi, P, Sette, C   +11 more
core   +2 more sources