Results 71 to 80 of about 23,772 (188)

Natural Variations in the Activity of Hydroxycinnamoyl Transferases Promote Accumulation of Metabolites Conferring Rice Resistance

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Plant‐derived secondary metabolites act as regulators of in planta defence. Plant phenylpropanoid metabolic compounds, including final metabolites such as lignin and flavonoids, and a few intermediate metabolites play critical roles in defence.
Dan Chen   +9 more
wiley   +1 more source

Lack of Influence of Spermine or Diet on Calf Spermine Oxidase Formation

open access: yesJournal of Dairy Science, 1965
Abstract Studies were conducted to ascertain the changes in blood plasma spermine oxidase activity in the young dairy calf as the animal developed. Results show that there is a steady increase in plasma spermine oxidase activity up until 40-60 days of age with no further increase.
E, UEYAMA, C L, DAVIS, M J, WOLIN
openaire   +2 more sources

Methyl Jasmonate Seed Priming Mitigates the Defence‐Growth Trade‐Off and Tailors Plant Response to Specific Pests

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Seed defence priming is emerging as a novel, cost‐efficient and environmentally safe tool for pest management. It has been proposed as a means to uncouple the defence‐growth trade‐off in plants by enhancing defence responses with minimal fitness costs, but the mechanisms underlying this role remain elusive.
Lucia Talavera‐Mateo   +5 more
wiley   +1 more source

A Combination of Xanthohumol and Ursolic Acid in the Diet Leads to Synergistic Inhibition of Prostate Cancer Progression

open access: yesMolecular Carcinogenesis, Volume 65, Issue 4, Page 508-522, April 2026.
ABSTRACT Prostate cancer (PCa) is the second most common cancer and second leading cause of cancer death for American men. Chemoprevention by using phytochemicals offers a promising approach to improve outcomes due to their ability to act on cancer cell metabolism and growth while maintaining low toxicity profiles.
Rachel Clark   +6 more
wiley   +1 more source

Rapid detection of spermine by using a cost-effective carbon nanostructured aptasensor

open access: yesNano TransMed
Spermine is a polyamine that participates in ion channel regulation and cell proliferation. It is considered a biomarker for pancreatic cancer. In this study, a carbon nanostructure-based aptasensor has been developed to rapidly detect spermine in ...
Howyn Tang   +3 more
doaj   +1 more source

Weight Loss During Obesity Provokes Asparaginase‐Associated Liver Steatosis and Endoplasmic Reticulum Stress

open access: yesThe FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Lean mice and DIO mice were fed either a low‐fat maintenance diet (MD) or a high‐fat obesogenic diet (OD) during pegylated asparaginase exposure. OD exacerbated asparaginase‐induced weight loss and modestly increased liver triglycerides and ER stress in lean mice.
Chintan T. Bhavsar   +9 more
wiley   +1 more source

Spermine Regulates Bone Homeostasis Through The Gut-Bone Axis

open access: yesInternational Dental Journal
Aim or purpose: This study aims to explore the specific mechanism by which spermine, a metabolite highly expressed in the saliva of patients with MRONJ, regulates bone homeostasis through the gut-bone axis.
Ruixue Jiang, Yuwei Deng
doaj   +1 more source

Metagenomic and biogenic amine changes in cassava fermentation for tucupi production using Pediococcus acidilactici starter culture

open access: yesJournal of the Science of Food and Agriculture, Volume 106, Issue 4, Page 2424-2436, 15 March 2026.
Abstract BACKGROUND The use of starter cultures is essential for producing fermented foods with desirable standardized characteristics and for preventing pathogens. Pediococcus acidilactici, isolated from cocoa fermentation, was used in the production of tucupi, a widely appreciated sauce made from the juice of cassava root (manipueira) in the ...
Danielle Gama Brício   +9 more
wiley   +1 more source

Polyamine metabolism changes in psoriasis

open access: yesIndian Journal of Dermatology, 2013
Introduction: Polyamines - putrescine, spermidine and spermine are polycationic compounds ubiquitous for all living organisms. They are essential for the cell growth and differentiation, the control of cell cycle progress, apoptosis, and cancerogenesis ...
Valentina Broshtilova   +2 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, Volume 20, Issue 3, Page 779-803, March 2026.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

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