Results 71 to 80 of about 863 (166)

Liver Protection of Hydroxytyrosol Mediated by Spexin and TRPM2

Journal of Contemporary Medicine, 2023
Background/Aim: In the study, the role of Spexin (SPX) and TRPM2 in the protective effect of Hydroxytyrosol (HT) in rats given Corn Syrup was evaluated. Material and Method: The rats were divided into 4 groups (6 rats in each) (Control, HT, Corn Syrup, Corn Syrup +HT). Rats were given 30% Corn Syrup with drinking water for 6 weeks. 4 ml/kg/day liquid
Elif ONAT, Nevin KOCAMAN
openaire   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors

British Journal of Pharmacology, Volume 182, Issue S1, Page S24-S151, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Anthony P. Davenport, Eamonn Kelly, Alasdair J. Gibb, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Maria Pia Abbracchio, George R. Abraham, Alexander Agoulnik, Wayne Alexander, Khaled Al‐hosaini, Magnus Bäck, Jillian G. Baker, Nicholas M. Barnes, Ross Bathgate, Jean‐Martin Beaulieu, Annette G. Beck‐Sickinger, Maik Behrens, Kirstie A. Bennett, Kenneth E. Bernstein, Bernhard Bettler, Nigel J. M. Birdsall, Victoria A. Blaho, Pascal Bonaventure, Francois Boulay, Corinne Bousquet, Hans Bräuner‐Osborne, Andrew J. Brown, Geoffrey Burnstock, Marta Busnelli, Girolamo Caló, Vanni Caruso, Justo P. Castaño, Kevin J. Catt, Stefania Ceruti, Paul Chazot, Nan Chiang, Bice Chini, Arthur Christopoulos, Jerold Chun, Antonia Cianciulli, Olivier Civelli, Lucie H. Clapp, Réjean Couture, Helen M. Cox, Zsolt Csaba, Claes Dahlgren, Frank M. Dautzenberg, Gordon Dent, Steven D. Douglas, Pascal Dournaud, Margarita L. Dubocovich, Satoru Eguchi, Emanuel Escher, Edward J. Filardo, Tung Fong, Huamei Fu Forsman, Marta Fumagalli, Raul R. Gainetdinov, Michael L. Garelja, Marc de Gasparo, Florence Gbahou, Craig Gerard, Marvin Gershengorn, Michelle Glass, David E. Gloriam, Fernand Gobeil, Theodore L. Goodfriend, Cyril Goudet, Lukas Grätz, Karen J. Gregory, Christian Gruber, Andrew L. Gundlach, Jörg Hamann, Julien Hanson, Deborah S. Hartman, Richard L. Hauger, Debbie L. Hay, Akos Heinemann, Laura Heitman, Deron R. Herr, Morley D. Hollenberg, Nicholas D. Holliday, Birgitte Holst, Mastgugu Horiuchi, Daniel Hoyer, László Hunyady, Ahsan Husain, Adriaan P. IJzerman, Tadashi Inagami, Paul A. Insel, Kenneth A. Jacobson, Laura H. Jacobson, Robert T. Jensen, Ralf Jockers, Deepa Jonnalagadda, Sadashiva Karnik, Klemens Kaupmann, Jacqueline Kemp, Charles Kennedy, Yasuyuki Kihara, Julia Kinsolving, Takio Kitazawa, Pawel Kozielewicz, Hans‐Jürgen Kreienkamp, Jyrki P. Kukkonen, Luxmichan Laishram, Tobias Langenhan, Christopher J. Langmead, Dan Larhammar, Katie Leach, Davide Lecca, John D. Lee, Susan E. Leeman, Jérôme Leprince, Rob Leurs, Xaria X. Li, Ines Liebscher, Stephen J. Lolait, Amelie Lupp, Robyn Macrae, Janet J. Maguire, Davide Malfacini, Maurice Manning, Davide Marangon, Kirill Martemyanov, Jean Mazella, Craig A. McArdle, Shlomo Melmed, Martin C. Michel, Laurence J. Miller, Vincenzo Mitolo, Bernard Mouillac, Christa E. Müller, Philip M. Murphy, Jean‐Louis Nahon, Richard R. Neubig, Tony Ngo, Xavier Norel, Duuamene Nyimanu, Anne‐Marie O’Carroll, Stefan Offermanns, Maria Antonietta Panaro, Marc Parmentier, Nicole Perry‐Hauser, Roger G. Pertwee, Jean‐Philippe Pin, Eric R. Prossnitz, Helena Chengxue Qin, Mark Quinn, Stefano Raffaele, Rithwik Ramachandran, Manisha Ray, Rainer K. Reinscheid, Alejandro Romeral Buzón, Philippe Rondard, Mette M. Rosenkilde, G. Enrico Rovati, Chiara Ruzza, Gareth J. Sanger, Nicole Scholz, Torsten Schöneberg, Gunnar Schulte, Stefan Schulz, Deborah L. Segaloff, Charles N. Serhan, Arun K. Shukla, Khuraijam Dhanachandra Singh, Craig M. Smith, Nicola J. Smith, Claudia Stäubert, Leigh A. Stoddart, Yukihiko Sugimoto, Roger Summers, Valerie P. Tan, David M. Thal, Walter ( Wally) Thomas, Pieter B. M. W. M. Timmermans, Kalyan Tirupula, Lawrence Toll, Giovanni Tulipano, Hamiyet Unal, Thomas Unger, Celine Valant, Patrick Vanderheyden, David Vaudry, Hubert Vaudry, Joseph G. Verbalis, Jean‐Pierre Vilardaga, Christopher S. Walker, Ji Ming Wang, Donald T. Ward, Hans‐Jürgen Wester, Gary B. Willars, Tom Lloyd Williams, Trent M. Woodruff, Huixian Wu, Cheng Yang, Chengcan Yao, Richard D. Ye, Nathan Zaidman   +206 more
wiley   +1 more source

Housing temperature influences exercise‐induced glucose regulation and expression of exerkines in mice

Experimental Physiology, Volume 110, Issue 8, Page 1099-1113, 1 August 2025.
Abstract The impact of housing temperature on exercise‐induced metabolic adaptations is not well understood, despite extensive research on the benefits of exercise for metabolic health. The aim of this study was to elucidate how housing temperatures influence the molecular responses and metabolic benefits of exercise in mice.
Zhijian Rao, Xue Geng, Peng Huang, Qiangman Wei, Shijie Liu, Chaoyi Qu, Jiexiu Zhao   +6 more
wiley   +1 more source

Metabolic Effect of Spexin on Obesity and Diabetes: A Mini Review

The Iraqi Journal of Medical Sciences
Spexin is an adipokine and neuropeptide that is extensively expressed in a number of tissues and organs, like the pancreas, fat, small intestine, liver, stomach, and other endocrine tissues to perform a variety of functions such as glucose and lipid ...
Sura A. Abdulsattar, Raghad H. Al-Ani , Tamara S. Naji   +2 more
doaj   +1 more source

Evaluation of spexin level in obese patients [PDF]

, 2020
Kaymaz, Ö. Obez Hastalarda Serum Speksin Düzeyinin Değerlendirilmesi, Enstitüler, Sağlık Bilimleri Enstitüsü, Tıbbi Biyokimya Anabilim Dalı Yüksek Lisans Tezi, Tekirdağ, 2020. Obezite sağlığımızı olumsuz etkileyen multifaktöriyel kompleks bir hastalıktır.
Kaymaz, Özlem
core   +1 more source

Neuropeptides: The Evergreen Jack‐of‐All‐Trades in Neuronal Circuit Development and Regulation

BioEssays, Volume 47, Issue 3, March 2025.
Neuropeptides provide an efficient alternative to fast neurotransmitters for synapses neurotransmission. Here, a perspective on the roles, eventual redundancy, and receptor‐level signal diversity of neuropeptides during neurodevelopment is provided through galanin as an example. Image shows thalamic neurons in Gal‐Cre:Ai9 mice. Courtesy of J.
Zsofia Hevesi, Tomas Hökfelt, Tibor Harkany   +2 more
wiley   +1 more source

Effect of eight weeks of aerobic and resistance training on adropin, spexin, and TNFα levels, as well as insulin resistance indices, in obese men with type 2 diabetes [PDF]

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2023
Introduction: Energy homeostasis as a metabolic control pathway can be investigated from different dimensions. The present study aimed to assess the effect of eight weeks of aerobic and resistance training on adropin, spexin, and TNFa, as well as insulin
Mahdiyeh Shamizadeh, Mohamad Reza Zolfaghari, Amir Fattahi   +2 more
doaj  

Spexin Protects Against Oxidative Stress-Induced Apoptosis of Sciatic Nerve Among Rats with Diabetic Peripheral Neuropathy [PDF]

Zagazig University Medical Journal
Background: Diabetic peripheral neuropathy (DPN) is considered among the most common consequences of diabetes mellitus (DM). Spexin-14 amino acid peptide hormone- is expressed in brain and peripheral tissues.
Sherein El-sayed, Sara Seada, Basma Elsayed, Hadeel Elsherbini   +3 more
doaj   +1 more source

Effects of combined aerobic and resistance training on the inflammatory profile of children with overweight/obesity: A randomized clinical trial

Pediatric Obesity, Volume 19, Issue 10, October 2024.
Summary Background We assessed the effects of a 20‐week combined (aerobic and resistance) exercise training programme on the inflammatory profile of prepubertal children with overweight or obesity. Methods Totally 109 participants (10.1 ± 1.1 years, 41% girls) were randomly allocated to an exercise or control group.
Jose J. Gil‐Cosano, Abel Plaza‐Florido, Luis Gracia‐Marco, Jairo H. Migueles, Cristina Cadenas‐Sanchez, Marcos Olvera‐Rojas, Esther Ubago‐Guisado, Idoia Labayen, Alejandro Lucia, Francisco B. Ortega   +9 more
wiley   +1 more source

Circulating Levels of Nesfatin-1 and Spexin in Children with Prader-Willi Syndrome during Growth Hormone Treatment and Dietary Intervention

, 2023
Background: Despite observable improvement in the treatment outcomes of patients with Prader-Willi syndrome (PWS), adequate weight control is still a clinical problem.
Joanna Gajewska, Małgorzata Strucińska, Jadwiga Ambroszkiewicz, Katarzyna Szamotulska, Magdalena Chełchowska, Witold Klemarczyk   +5 more
core   +1 more source