Results 51 to 60 of about 863 (166)

The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors

open access: yesBritish Journal of Pharmacology, Volume 180, Issue S2, Page S23-S144, October 2023., 2023
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands.
Stephen P. H. Alexander   +165 more
wiley   +1 more source

Spexin-expressing neurons in the magnocellular nuclei of the human hypothalamus [PDF]

open access: yesJournal of Chemical Neuroanatomy, 2021
Neuropeptides are involved in numerous brain activities being responsible for a wide spectrum of higher mental functions. The purpose of this concise, structural and qualitative investigation was to map the possible immunoreactivity of the novel neuropeptide spexin (SPX) within the human magnocellular hypothalamus.
Pałasz, A.   +11 more
openaire   +4 more sources

Serum spexin concentration, body condition score and markers of obesity in dogs

open access: yesJournal of Veterinary Internal Medicine, 2021
Background Spexin (SPX) is a peptide hormone that regulates body weight, adipose tissue metabolism, and food intake. Hypothesis Serum SPX concentration correlates with body condition score (BCS) and markers of obesity in dogs. Animals Fifty‐seven dogs of
Pawel Antoni Kolodziejski   +8 more
doaj   +1 more source

Decreased Circulating Levels of Spexin in Obese Children [PDF]

open access: yesThe Journal of Clinical Endocrinology & Metabolism, 2016
Spexin is a novel peptide that is implicated in obesity and related energy homeostasis in animals and adult humans. Little is known about its role in children.The aim of the current study was to determine the potential role of Spexin in obese children and explore its relationships with various cardiometabolic risk factors.This was a cross-sectional ...
Seema, Kumar   +5 more
openaire   +2 more sources

Short-term changes and correlations of plasma spexin, kisspeptin, and galanin levels after laparoscopic sleeve gastrectomy

open access: yes, 2021
Purpose To determine the circulating levels of spexin, kisspeptin, galanin, and the correlations between these peptides after laparoscopic sleeve gastrectomy (LSG). Methods The plasma levels of the spexin, kisspeptin, and galanin and metabolic parameters
Atabey, Mustafa   +7 more
core   +1 more source

The protective effects of humanin in rats with experimental myocardial infarction: The role of asprosin and spexin

open access: yesHeliyon, 2023
Objective: In this study, by applying humanin (HN) before myocardial infarction (MI) in rats, its protection in MI and the possible roles in asprosin and spexin were investigated.
Elif Onat, Nevin Kocaman, Serhat Hancer
doaj   +1 more source

Mouse Spexin: (II) Functional Role as a Satiety Factor inhibiting Food Intake by Regulatory Actions Within the Hypothalamus

open access: yesFrontiers in Endocrinology, 2021
Spexin (SPX) is a pleiotropic peptide with highly conserved protein sequence from fish to mammals and its biological actions are mediated by GalR2/GalR3 receptors expressed in target tissues.
Matthew K. H. Wong   +6 more
doaj   +1 more source

Adropin and spexin hormones regulate the systemic inflammation in adenine-induced chronic kidney failure in rat

open access: yesChinese Journal of Physiology, 2021
Chronic kidney disease is one of the major global health problems. Chronic renal failure is stimulated by many cytokines and chemokines. Adropin and spexin (SPX) are peptides hormones.
Gulsun Memi, Burak Yazgan
doaj   +1 more source

Spexin Levels Are Associated with Metabolic Syndrome Components

open access: yesDisease Markers, 2018
Background. Spexin (SPX) is a novel peptide that is implicated in obesity and related energy homeostasis in animals and adult humans. Little is known about its role in adults’ overall cardiometabolic health. The aim of the study was to determine whether circulating levels of spexin (SPX) is associated with components of metabolic syndrome (MetS ...
Nasser M. Al-Daghri   +5 more
openaire   +2 more sources

Spexin and a novel cichlid-specific spexin paralog both inhibit FSH and LH through a specific galanin receptor (Galr2b) in tilapia [PDF]

open access: yesFrontiers in Endocrinology, 2019
Abstract Spexin (SPX) is a 14 amino acid peptide hormone that has pleiotropic functions across vertebrates, one of which is involvement in the brain-pituitary-gonad axis of fish. SPX(1) has been identified in each class of vertebrates, and a second SPX (named SPX2) has been found in some non-mammalian species. We have
Cohen, Yaron   +4 more
openaire   +3 more sources

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