Results 1 to 10 of about 9,343 (242)

Sphinganine-Analog Mycotoxins (SAMs): Chemical Structures, Bioactivities, and Genetic Controls [PDF]

Journal of Fungi, 2020
Sphinganine-analog mycotoxins (SAMs) including fumonisins and A. alternata f. sp. Lycopersici (AAL) toxins are a group of related mycotoxins produced by plant pathogenic fungi in the Fusarium genus and in Alternaria alternata f. sp.
Jia Chen, Zhimin Li, Yi Cheng, Chunsheng Gao, Litao Guo, Tuhong Wang, Jianping Xu   +6 more
doaj   +5 more sources

Dietary sphinganine is selectively assimilated by members of the mammalian gut microbiome [PDF]

Journal of Lipid Research, 2021
Functions of the gut microbiome have a growing number of implications for host metabolic health, with diet being one of the most significant influences on microbiome composition.
Min-Ting Lee, Henry H. Le, Elizabeth L. Johnson   +2 more
doaj   +2 more sources

Preparation of anti-vicinal amino alcohols: asymmetric synthesis of D-erythro-Sphinganine, (+)-spisulosine and D-ribo-phytosphingosine [PDF]

, 2013
Two variations of the Overman rearrangement have been developed for the highly selective synthesis of anti-vicinal amino alcohol natural products. A MOM-ether directed palladium(II)-catalyzed rearrangement of an allylic trichloroacetimidate was used as ...
Abraham E., Ahmed M. Zaed, Ait-Youcef R., Allepuz A. C., Amarante G. W., Andrew Sutherland, Barrett A. G. M., Bernet B., Blanchette M. A., Cai Y., Cai Y., Chen B.-S., Cook G. R., Corey E. J., Corey E. J., Cuadros R., Davies S. G., Devi T. J., Dickson R. C., Dinda S. K., Enders D., Ewen D. D. Calder, Fanning K. N., Fernandes R. A., Ghosal P., Hertweck C., Hoffmann R. W., Howell A. R., Hubieki M. P., Jamieson A. G., Jamieson A. G., Jamieson A. G., Jamieson A. G., Kokatla H. P., Kolb H. C., Kolter T., Koskinen P. M., Lee S. I., Lipshutz B. H., Liu Z., Llaveria J., Lombardo M., Luo S.-Y., Malik G., Martinková M., Modrak D. E., Morales-Serna J. A., Murakami T., Naidu S. V., Ndakala A. J., Ndonye R. M., Perali R. S., Prabhakar P., Rodriguez-Lafrasse C., Schneiter R., Sengupta S., Snook C. F., So R. C., Summers S. A., Swift M. D., Séguin C., Watanabe M., Xarnod C., Xu K., Yoon H. J., Yun J. M., Zaed A., Zaed A. M.   +67 more
core   +2 more sources

Effect of the multifunctional cosmetic ingredient sphinganine on hair loss in men and women with diffuse hair reduction

Clinical, Cosmetic and Investigational Dermatology, 2016
Nicole Gerlach,1,* Matthias Mentel,2,* Tim Köhler,2 Benjamin Tuchscherer,2 Birgit Garbe,1 Jasmina Ülker,1 Hagen Tronnier,1 Ulrike Heinrich,1 Mike Farwick2 1DermaTronnier GmbH & Co. KG, Institute for Experimental Dermatology, Witten/Herdecke
Gerlach N, Mentel M, Köhler T, Tuchscherer B, Garbe B, Ülker J, Tronnier H, Heinrich U, Farwick M   +8 more
doaj   +3 more sources

Conversion of erythro-D-sphinganine to its [1-2H1] and [1-3H1] derivatives.

Journal of Lipid Research, 1984
A convenient chemical synthesis of erythro-D-[1-2H1] sphinganine and erythro-D-[1-3H1]sphinganine is described. The approach utilizes a stereospecific starting material (natural sphinganine prepared from bovine brain sphingomyelin) and applies a sequence
M W Crossman, C B Hirschberg
doaj   +2 more sources

Isolation and Quantification of Sphingosine and Sphinganine from Rat Serum Revealed Gender Differences [PDF]

Biomolecules, 2019
Sphingolipids are an important group of lipids that play crucial roles in living cells, facilitating cell recognition, signal transduction and endocytosis.
Graham Brogden, Diab M. Husein, Pablo Steinberg, Hassan Y. Naim   +3 more
doaj   +2 more sources

A novel fluorescein sodium-based screening platform for the identification of sphingoid base-producing Wickerhamomyces ciferrii mutants [PDF]

Frontiers in Bioengineering and Biotechnology
The efficient identification of microbial strains capable of producing rare sphingoid bases, such as sphingosine and sphinganine, is critical for advancing microbial fermentation processes and addressing increasing industrial demands.
Jun Su Kang, Seong-Rae Lee, Minju Lee, Eunha Kim, Pyung Cheon Lee   +4 more
doaj   +2 more sources

Sphinganine recruits TLR4 adaptors in macrophages and promotes inflammation in murine models of sepsis and melanoma [PDF]

Nature Communications
After recognizing its ligand lipopolysaccharide, Toll-like receptor 4 (TLR4) recruits adaptor proteins to the cell membrane, thereby initiating downstream signaling and triggering inflammation.
Marvin Hering, Alaa Madi, Roger Sandhoff, Sicong Ma, Jingxia Wu, Alessa Mieg, Karsten Richter, Kerstin Mohr, Nora Knabe, Diana Stichling, Gernot Poschet, Felix Bestvater, Larissa Frank, Jochen Utikal, Viktor Umansky, Guoliang Cui   +15 more
doaj   +2 more sources

Sphinganine as a potentially relevant metabolite in pulmonary involvement of primary Sjögren's syndrome. [PDF]

J Lipid Res
Cui T, Geng Z, Wang N, Luo J, Li Z.
europepmc   +2 more sources

Identification and characterization of 3-ketosphinganine reductase activity encoded at the BT_0972 locus in Bacteroides thetaiotaomicron

Journal of Lipid Research, 2022
Bacterial sphingolipid synthesis is important for the fitness of gut commensal bacteria with an implied potential for regulating mammalian host physiology.
Min-Ting Lee, Henry H. Le, Kevin R. Besler, Elizabeth L. Johnson   +3 more
doaj   +1 more source