Results 101 to 110 of about 9,343 (242)
Hereditary sensory and autonomic neuropathy type 1 (HSANI) caused by a novel mutation in SPTLC2. [PDF]
, 2013 To describe the clinical and neurophysiologic phenotype of a family with hereditary sensory and autonomic neuropathy type 1 (HSANI) due to a novel mutation in SPTLC2 and to characterize the biochemical properties of this ...
Blake, J +10 more
core +1 more source
MedComm, Volume 6, Issue 10, October 2025.Salivary metabolomics offers a noninvasive and effective approach for early disease detection and monitoring. Salivary metabolites reflect systemic metabolism, inflammation, and external factors such as diet and stress. Advance in bioinformatics and machine learning facilitates the identification of metabolic biomarkers with high diagnostic accuracy ...
Xinyuan Zhao +8 more
wiley +1 more source
Activity of 3-ketosphinganine synthase during differentiation and aging of neuronal cells in culture
Journal of Lipid Research, 1997 Changes in the enzyme 3-ketosphinganine synthase activity in rat cerebellar granule cells in culture were studied during differentiation and aging. The enzyme activity with palmitoyl-CoA and stearoyl-CoA, precursors of, respectively, C18-sphinganine and ...
V Chigorno +3 more
doaj +1 more source
Ceramides and mitochondrial fatty acid oxidation in obesity [PDF]
, 2017 : Obesity is an epidemic, complex disease that is characterized by increased glucose, lipids, and low-grade inflammation in the circulation, among other factors.
Casals i Farré, Núria +3 more
core +1 more source
Results in ChemistryAcquired immune deficiency syndrome (AIDS) has been shown to not only attack the body's immune system but also to cause metabolic disorders. Highly active anti-retroviral therapy (HAART) is the main treatment for AIDS, but it can also affect the human ...
Aoxin Ma +7 more
doaj +1 more source
Marine Drugs, 2013 Severe toxicity was detected in mussels from Bizerte Lagoon (Northern Tunisia) using routine mouse bioassays for detecting diarrheic and paralytic toxins not associated to classical phytoplankton blooming. The atypical toxicity was characterized by rapid
Riadh Marrouchi +6 more
doaj +1 more source
A high-fat diet containing whole walnuts (Juglans regia) reduces tumour size and growth along with plasma insulin-like growth factor 1 in the transgenic adenocarcinoma of the mouse prostate model. [PDF]
, 2012 Prostate cancer (PCa) has been linked to fat intake, but the effects of both different dietary fat levels and types remain inconsistent and incompletely characterised.
Cross, Carroll E +6 more
core +1 more source
Marine Drugs, 2017 Liposomal circular dichroism (L-CD) of acyclic amino alcohols exhibit amplification of Cotton effects when measured in highly uniform, unilamellar liposomes.
Tadeusz F. Molinski +2 more
doaj +1 more source
Long-chain bases in the sphingolipids of atherosclerotic human aorta
Journal of Lipid Research, 1969 Long-chain bases were prepared from human aorta sphingomyelin by a combined enzymatic hydrolysis-alkaline hydrolysis procedure and these bases were isolated by thin-layer chromatography.
R.V. Panganamala +2 more
doaj +1 more source
Plasma deoxysphingolipids: a novel class of biomarkers for the metabolic syndrome? [PDF]
, 2018 Aims/hypothesis: Sphingolipid synthesis is typically initiated by the conjugation of l-serine and palmitoyl-CoA, a reaction catalysed by serine palmitoyltransferase (SPT). SPT can also metabolise other acyl-CoAs (C12 to C18) and other amino acids such as
Bianchi, R. +10 more
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